Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607387 | 0.81 | ALDH1A1 (0.46) | MAPTLMNAKDM4ENPC1RAB9A | |
| SCHEMBL16720499 | 0.79 | CYP2A6 (0.48) | MAPTLMNAKDM4ENPC1RAB9A | |
| SCHEMBL9987990 | 0.79 | ESR1 (0.42) | MAPTLMNAKDM4ENPC1RAB9A | |
| SCHEMBL16719718 | 0.78 | ATM (0.39) | MAPTLMNAKDM4ENPC1RAB9A | |
| SCHEMBL16719811 | 0.78 | QDPR (0.32) | QDPRMAPTLMNAKDM4ENPC1 | |
| SCHEMBL9650164 | 0.76 | NPC1 (0.35) | MAPTLMNAKDM4ENPC1RAB9A | |
| SCHEMBL7852621 | 0.76 | MAPT (0.39) | MAPTLMNANOTUMKDM4ENPC1 | |
| SCHEMBL9988099 | 0.76 | TRPA1 (0.37) | MAPTLMNAKDM4ENPC1RAB9A | |
| SCHEMBL7855064 | 0.76 | LMNA (0.39) | MAPTLMNANOTUMKDM4ENPC1 | |
| SCHEMBL16720201 | 0.76 | ALOX5 (0.45) | MAPTLMNAKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |