Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CDC42 | P60953 | 1/20 | 0.39 |
| ▸ | RAC1 | P63000 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1673370 | 0.87 | NPSR1 (0.43) | ALOX5NPSR1BMP1SLC6A2SLC6A4 | |
| SCHEMBL28656346 | 0.79 | NPSR1 (0.46) | ALOX5NPSR1BMP1PTGS2AKR1C3 | |
| SCHEMBL836811 | 0.78 | NPY5R (0.49) | ALOX5NPSR1BMP1APPCYP2C19 | |
| SCHEMBL17603763 | 0.75 | BMP1 (0.43) | NPSR1BMP1KMT2AACP3L3MBTL1 | |
| SCHEMBL6349734 | 0.74 | TAS1R3 (0.43) | ALOX5NPSR1BMP1SLC6A2SLC6A4 | |
| SCHEMBL16991743 | 0.74 | ALDH1A1 (0.49) | NPSR1MEN1KMT2ACYP1A2RAB9A | |
| SCHEMBL16991741 | 0.74 | ALDH1A1 (0.49) | NPSR1MEN1KMT2ACYP1A2RAB9A | |
| SCHEMBL5862818 | 0.72 | BMP1 (0.41) | NPSR1BMP1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL14860429 | 0.71 | CYP1A2 (0.46) | ALOX5NPSR1CYP2C19CYP1A2GRM8 | |
| SCHEMBL1282309 | 0.71 | ADRB2 (0.42) | SLC6A4CYP2C19MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092501-A1 | NOVEL INHIBITORS | PROBIODRUG AG (DE) | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092501-A1 | NOVEL INHIBITORS | GLUL, QPCT, GLS | ALOX5 858/4885NPSR1 3094/4885BMP1 3133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.