Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SCD5 | Q86SK9 | 5/20 | 0.49 |
| ▸ | SPR | P35270 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16735634 | 0.93 | KDM4C (0.54) | POLBSCD5SPRKDM4CSCD | |
| SCHEMBL16735667 | 0.85 | POLB (0.51) | POLBALDH1A1RXFP1 | |
| SCHEMBL16735578 | 0.83 | POLB (0.56) | POLBALDH1A1RXFP1 | |
| SCHEMBL16735647 | 0.83 | POLB (0.49) | POLBSPRALDH1A1RXFP1 | |
| SCHEMBL16735593 | 0.83 | RXFP1 (0.56) | POLBSPRRXFP1 | |
| SCHEMBL31428431 | 0.81 | CAPN1 (0.55) | SCD5CA12CA1CA2CA7 | |
| SCHEMBL16735658 | 0.80 | POLB (0.53) | POLBALDH1A1 | |
| SCHEMBL16735662 | 0.79 | HSP90AA1 (0.57) | SCD5SCDALDH1A1 | |
| SCHEMBL16735619 | 0.79 | POLB (0.52) | POLBL3MBTL1RXFP1 | |
| SCHEMBL16735636 | 0.78 | HSP90AA1 (0.62) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519505-B1 | TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF | POLICHEM SA (LU) | 2015-05-27 | — | — | EP | claimed |