Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RBP4 | P02753 | 1/20 | 0.43 |
| ▸ | SPR | P35270 | 12/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16735647 | 0.88 | POLB (0.49) | RXFP1POLBSPRHTR2AHTR2C | |
| SCHEMBL16735667 | 0.86 | POLB (0.51) | RXFP1POLBHPGD | |
| SCHEMBL16735578 | 0.84 | POLB (0.56) | RXFP1POLBHPGD | |
| SCHEMBL16735605 | 0.83 | POLB (0.51) | RXFP1POLBSPR | |
| SCHEMBL16735658 | 0.81 | POLB (0.53) | POLB | |
| SCHEMBL16735619 | 0.80 | POLB (0.52) | RXFP1POLBHPGD | |
| SCHEMBL2143807 | 0.79 | ALDH1A1 (0.51) | RXFP1HTR2AHTR2C | |
| SCHEMBL16735634 | 0.79 | KDM4C (0.54) | RXFP1POLBSPR | |
| SCHEMBL16735663 | 0.79 | RXFP1 (0.45) | RXFP1POLBHCRTR1HCRTR2 | |
| SCHEMBL16735639 | 0.79 | RXFP1 (0.46) | RXFP1POLBHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519505-B1 | TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF | POLICHEM SA (LU) | 2015-05-27 | — | — | EP | claimed |