Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | USP8 | P40818 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16740415 | 0.83 | MAOA (0.39) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL16740341 | 0.81 | HTR1A (0.36) | HTR1AADRA1DADRA1AADRA1BHSD17B10 | |
| SCHEMBL15088139 | 0.79 | HTR1A (0.38) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL16744462 | 0.79 | HTR1A (0.38) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL16740382 | 0.76 | RAB9A (0.40) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL16740381 | 0.76 | RAB9A (0.40) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL16740340 | 0.76 | AR (0.38) | ARUSP8KDM4EALDH1A1HPGD | |
| SCHEMBL29248916 | 0.75 | ATP4A (0.47) | MAOBHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL2944970 | 0.74 | USP8 (0.41) | MAOBUSP8HTR1AADRA1DADRA1A | |
| SCHEMBL22551784 | 0.70 | USP8 (0.43) | ARUSP8MAPTHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10010535-B2 | Desferrithiocin analogs and uses thereof | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-07-03 | — | — | US | disclosed |
| US-20160289223-A1 | DESFERRITHIOCIN ANALOGS AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2016-10-06 | — | — | US | disclosed |
| US-20160289223-A1 | DESFERRITHIOCIN ANALOGS AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2016-10-06 | — | — | US | disclosed |
| EP-3071201-A1 | DESFERRITHIOCIN ANALOGS AND USES THEREOF | University of Florida Research Foundation, Inc. (US) | 2016-09-28 | — | — | EP | disclosed |
| WO-2015077655-A1 | DESFERRITHIOCIN ANALOGS AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-05-28 | — | — | WO | disclosed |
| WO-2015077655-A1 | DESFERRITHIOCIN ANALOGS AND USES THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10010535-B2 | Desferrithiocin analogs and uses thereof | FECH, TFRC, FTH1 | AR 2850/4885MAOB 1855/4885USP8 4281/4885 |
| US-20160289223-A1 | DESFERRITHIOCIN ANALOGS AND USES THEREOF | FECH, TFRC, FTH1 | AR 2850/4885MAOB 1855/4885USP8 4281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.