Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | DRD3 | P35462 | 3/20 | 0.56 |
| ▸ | DRD4 | P21917 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5252735 | 0.93 | DRD2 (0.55) | DRD2DRD3DRD4MEN1LMNA | |
| SCHEMBL5248320 | 0.91 | DRD2 (0.52) | DRD2DRD3DRD4MEN1LMNA | |
| SCHEMBL10338308 | 0.87 | MEN1 (0.60) | DRD2DRD3DRD4MEN1LMNA | |
| SCHEMBL11093336 | 0.87 | KCNA3 (0.52) | DRD2DRD3DRD4CYP2D6L3MBTL1 | |
| SCHEMBL9114592 | 0.85 | CYP1A2 (0.63) | DRD2DRD3DRD4MEN1LMNA | |
| SCHEMBL9047325 | 0.83 | TSHR (0.53) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL28924895 | 0.83 | DRD2 (0.42) | DRD2DRD3DRD4MEN1LMNA | |
| SCHEMBL28387678 | 0.82 | DRD2 (0.43) | DRD2DRD3DRD4MEN1LMNA | |
| SCHEMBL4270834 | 0.81 | TSHR (0.64) | DRD2DRD3DRD4CYP1A2CYP2D6 | |
| SCHEMBL11096825 | 0.80 | CYP3A4 (0.52) | CYP1A2CYP2D6CYP2C19HRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898581-B1 | SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES SYNTHESIS | INTRA CELLULAR THERAPIES INC (US) | 2025-08-27 | — | — | EP | claimed |
| US-12297200-B2 | Substituted heterocycle fused gamma-carbolines synthesis | INTRA-CELLULAR THERAPIES, INC. (US) | 2025-05-13 | — | — | US | claimed |
| CN-116332580-B | Preparation method for preparing simulated stone by using chrome-containing leather ash | 烟台大学 | 2025-02-18 | — | — | CN | claimed |
| US-20240279228-A1 | NOVEL SALTS AND CRYSTALS | INTRA-CELLULAR THERAPIES, INC. | 2024-08-22 | — | — | US | claimed |
| CN-113195450-B | Synthesis of substituted heterocycle fused gamma-carbolines | 细胞内治疗公司 | 2024-04-26 | — | — | CN | claimed |
| EP-4352057-A1 | NOVEL SALTS AND CRYSTALS | Intra-Cellular Therapies, Inc. (US) | 2024-04-17 | — | — | EP | claimed |
| CN-117425652-A | Novel salts and crystals | 细胞内治疗公司 | 2024-01-19 | — | — | CN | claimed |
| CN-116332580-A | Preparation method for preparing simulated stone by using chrome-containing leather ash | 烟台大学 | 2023-06-27 | — | — | CN | claimed |
| WO-2022261633-A1 | NOVEL SALTS AND CRYSTALS | INTRA-CELLULAR THERAPIES, INC. (US) | 2022-12-15 | — | — | WO | claimed |
| EP-2134710-B1 | SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES SYNTHESIS | INTRA CELLULAR THERAPIES INC (US) | 2020-02-12 | — | — | EP | claimed |
| US-9751883-B2 | Preparation of certain [((6BR,10AS)-2,3,6B,7,8,9,10, 10A-octahydro-1H-pyrido[3′,4′:4,5]pyrrolo [1,2,3-de]quinoxalines and pharmaceutically acceptable salts thereof | INTRA-CELLULAR THERAPIES, INC. (US) | 2017-09-05 | — | — | US | claimed |
| US-20140364609-A1 | SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES SYNTHESIS | INTRA-CELLULAR THERAPIES, INC. | 2014-12-11 | — | — | US | claimed |
| CN-103626766-A | Substituted heterocycle fused gamma-carbolines synthesis | INTRA CELLULAR THERAPIES INC | 2014-03-12 | — | — | CN | claimed |
| CN-101796051-B | Synthesis of substituted heterocycle fused gamma-carbolines | INTRA CELLULAR THERAPIES INC | 2013-11-06 | — | — | CN | claimed |
| EP-0076530-B1 | NOVEL N-(3-HYDROXY-4-PIPERIDINYL)BENZAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1985-12-11 | — | — | EP | claimed |
| EP-0076530-A2 | Novel N-(3-hydroxy-4-piperidinyl)benzamide derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1983-04-13 | — | — | EP | claimed |
| US-20260098040-A1 | SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES SYNTHESIS | INTRA CELLULAR THERAPIES INC (US) | 2026-04-09 | — | — | US | disclosed |
| EP-3609891-B1 | SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES SYNTHESIS | INTRA CELLULAR THERAPIES INC (US) | 2026-02-11 | — | — | EP | disclosed |
| US-4010280-A | PHENOXYALKYLAMINE DERIVATIVES AND PREPARATION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-03-01 | — | — | US | disclosed |
| US-3965106-A | 3-Phenoxypropylamine derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279228-A1 | NOVEL SALTS AND CRYSTALS | SLC6A12, UACA, CYCS | DRD2 468/4885DRD3 463/4885DRD4 255/4885 |
| US-20140364609-A1 | SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES SYNTHESIS | HCCS, CYCS, CBR3 | DRD2 209/4885DRD3 350/4885DRD4 166/4885 |
| US-20260098040-A1 | SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES SYNTHESIS | KCNH2, KCNH3, KCNH1 | DRD2 660/4885DRD3 941/4885DRD4 1161/4885 |
| US-12297200-B2 | Substituted heterocycle fused gamma-carbolines synthesis | HCCS, CYCS, CBR3 | DRD2 221/4885DRD3 372/4885DRD4 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.