SCHEMBL16767246

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17752427	0.81	PRNP (0.45)	HTTADRB2CYP1A1CYP1A2CYP1B1
	SCHEMBL72673	0.78	KDM4E (0.47)	HTTAPPADORA2ADCPSADORA3
	SCHEMBL861205	0.78	CYP1A1 (0.50)	CYP1A1CYP1A2CYP1B1APPADORA2A
	SCHEMBL515743	0.78	HTT (0.50)	HTTADRB2CYP1A2RXFP1BCHE
	SCHEMBL13696895	0.78	ACHE (0.67)	HTTADRB2CYP1A1CYP1A2CYP1B1
	SCHEMBL18647352	0.78	PRNP (0.62)	ADORA2AADORA3ADORA2BADORA1RXFP1
	SCHEMBL72801	0.78	DCPS (0.64)	HTTCYP1A1CYP1A2CYP1B1APP
	SCHEMBL29583288	0.78	DCPS (0.64)	HTTCYP1A1CYP1A2CYP1B1APP
	SCHEMBL4358438	0.77	HTT (0.68)	HTTADRB2ADORA2ADCPS
	SCHEMBL29649743	0.77	HTT (0.68)	HTTADRB2ADORA2ADCPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.