Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17752901 | 0.87 | HTT (0.45) | HTTNT5EKMT2AGAARXFP1 | |
| SCHEMBL17752895 | 0.85 | PTGES (0.41) | HTTNT5ECYP1A2CYP2C19MAPT | |
| SCHEMBL17752427 | 0.81 | PRNP (0.45) | HTTNT5EKMT2ARXFP1CYP1A2 | |
| SCHEMBL3118975 | 0.78 | RXFP1 (0.51) | HTTNT5EKMT2AGAARXFP1 | |
| SCHEMBL18647352 | 0.78 | PRNP (0.62) | KMT2ARXFP1MAPTPRNPMEN1 | |
| SCHEMBL16767246 | 0.78 | HTT (0.59) | HTTKMT2ARXFP1CYP1A2PRNP | |
| SCHEMBL3856320 | 0.78 | MAOA (0.67) | HTTNT5EKMT2AGAARXFP1 | |
| SCHEMBL516091 | 0.78 | TDP1 (0.59) | HTTKMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL3497699 | 0.77 | HTT (0.49) | HTTNT5EKMT2ARXFP1CYP1A2 | |
| SCHEMBL182719 | 0.77 | HTT (0.68) | HTTNT5EKMT2AGAARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151020-A1 | HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE | WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) | 2023-05-18 | — | — | US | disclosed |
| US-20230151020-A1 | HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE | WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) | 2023-05-18 | — | — | US | disclosed |
| EP-3569606-B1 | METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF | UNIVERSAL DISPLAY CORP (US) | 2022-01-05 | — | — | EP | disclosed |
| US-10978649-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2021-04-13 | — | — | US | disclosed |
| US-20200350504-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2020-11-05 | — | — | US | disclosed |
| US-10749121-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2020-08-18 | — | — | US | disclosed |
| EP-3569606-A1 | METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF | Universal Display Corporation (US) | 2019-11-20 | — | — | EP | disclosed |
| US-20190341563-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2019-11-07 | — | — | US | disclosed |
| US-10403831-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2019-09-03 | — | — | US | disclosed |
| EP-2399922-B1 | Metal complexes of cyclometallated imidazo(1,2-f) phenanthridine and diimidazo(1,2-A;1',2'-C)quinazoline ligands and isoelectronic and benzannulated analogs therof | UNIVERSAL DISPLAY CORP (US) | 2019-06-26 | — | — | EP | disclosed |
| EP-2243785-A1 | Phosphorescent condensed ring carbene metal complexes for use in organic light emitting devices | Universal Display Corporation (US) | 2010-10-27 | — | — | EP | disclosed |
| CN-101415718-A | Cyclometallated imidazo [1 ] s | UNIVERSAL DISPLAY CORP (US) | 2009-04-22 | — | — | CN | disclosed |
| WO-2008156879-A1 | BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS | UNIVERSAL DISPLAY CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |
| US-20080297033-A1 | BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS | UNIVERSAL DISPLAY CORPORATION | 2008-12-04 | — | — | US | disclosed |
| EP-1981898-A2 | METAL COMPLEXES OF CYCLOMETALLATED IMIDAZOÝ1,2-f¨PHENANTHRIDINE AND DIIMIDAZOÝ1,2-A:1',2'-C¨QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF | Universal Display Corporation (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007095118-A2 | METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f]PHENANTHRIDINE AND DIIMIDAZO[1,2-A:1',2'-C]QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF | UNIVERSAL DISPLAY CORPORATION (US) | 2007-08-23 | — | — | WO | disclosed |
| US-20070190359-A1 | Metal complexes of cyclometallated imidazo[1,2-ƒ]phenanthridine and diimidazo[1,2-a:1',2'-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof | UNIVERSAL DISPLAY CORPORATION | 2007-08-16 | — | — | US | disclosed |
| US-20070072842-A1 | 6-Alkenyl and 6-phenylalkyl substituted 2-quinolinones and 2-quinoxalinones as poly(adpribose) polymerase inhibitors | JANSSEN-CILAG (FR) | 2007-03-29 | — | — | US | disclosed |
| EP-1687277-A1 | 6-ALKENYL AND 6-PHENYLALKYL SUBSTITUTED 2-QUINOLINONES AND 2-QUINOXALINONES AS POLY(ADP-RIBOSE) POLYMERASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005054201-A1 | 6-ALKENYL AND 6-PHENYLALKYL SUBSTITUTED 2-QUINOLINONES AND 2-QUINOXALINONES AS POLY(ADP-RIBOSE) POLYMERASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072842-A1 | 6-Alkenyl and 6-phenylalkyl substituted 2-quinolinones and 2-quinoxalinones as poly(adpribose) polymerase inhibitors | PARP1, PARP6, PARP2 | HTT 1971/4885NT5E 924/4885KMT2A 744/4885 |
| US-20190341563-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | LIG1, L1CAM, LIG3 | HTT 2928/4885NT5E 1916/4885KMT2A 1979/4885 |
| US-10978649-B2 | Organic electroluminescent materials and devices | NR2C2, NR2E3, NCOA2 | HTT 4481/4885NT5E 3637/4885KMT2A 838/4885 |
| US-20080297033-A1 | BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS | IK, CRY1, MAP1LC3C | HTT 3124/4885NT5E 2105/4885KMT2A 1971/4885 |
| US-20230151020-A1 | HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE | OCIAD1, OCIAD2, EHD1 | HTT 26/4885NT5E 2007/4885KMT2A 3038/4885 |
| US-10749121-B2 | Organic electroluminescent materials and devices | LIG1, L1CAM, LIG3 | HTT 2928/4885NT5E 1916/4885KMT2A 1979/4885 |
| US-10403831-B2 | Organic electroluminescent materials and devices | LIG1, L1CAM, LIG3 | HTT 2928/4885NT5E 1916/4885KMT2A 1979/4885 |
| US-20200350504-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | NR2C2, NR2E3, NCOA2 | HTT 4481/4885NT5E 3637/4885KMT2A 838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.