Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491103 | 0.83 | CES2 (0.51) | CXCL8PTGS2PSEN1PSEN2APH1B | |
| SCHEMBL15568192 | 0.81 | CXCL8 (0.59) | CXCL8PTGS2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15568736 | 0.81 | CXCL8 (0.59) | CXCL8PTGS2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2111867 | 0.81 | CXCL8 (0.59) | CXCL8PTGS2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29718684 | 0.81 | CXCL8 (0.63) | CXCL8PTGS2MEN1KMT2AMMP1 | |
| SCHEMBL5672222 | 0.81 | CXCL8 (0.63) | CXCL8PTGS2MEN1KMT2AMMP1 | |
| SCHEMBL663906 | 0.81 | CXCL8 (0.63) | CXCL8PTGS2MEN1KMT2AMMP1 | |
| SCHEMBL4659044 | 0.81 | CXCL8 (0.63) | CXCL8PTGS2MEN1KMT2AMMP1 | |
| SCHEMBL24311424 | 0.80 | CFD (0.46) | CXCL8CFDNOTUMCYP1A2CYP3A4 | |
| SCHEMBL23972297 | 0.80 | FABP4 (0.47) | CXCL8CFDNOTUMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7923573-B2 | Benzene compound having 2 or more substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-12 | — | — | US | disclosed |