Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16794889 | 0.79 | NTRK1 (0.40) | NTRK1ALOX5KMT2AMEN1CA1 | |
| SCHEMBL16814655 | 0.78 | ALDH1A1 (0.44) | NTRK1ALOX5GAAKMT2AMEN1 | |
| SCHEMBL16794891 | 0.76 | NTRK1 (0.41) | NTRK1ALOX5GAAKMT2AMEN1 | |
| SCHEMBL14397606 | 0.75 | ALDH1A1 (0.51) | NTRK1GAAKMT2AMEN1L3MBTL1 | |
| SCHEMBL16794875 | 0.71 | NTRK1 (0.37) | NTRK1ALOX5TUBB4ATUBBTUBA3C | |
| SCHEMBL16794815 | 0.71 | PKM (0.41) | NOD2NOD1NTRK1PSEN1PSEN2 | |
| SCHEMBL16794967 | 0.70 | NTRK1 (0.48) | NTRK1ALOX5TUBB4ATUBBTUBA3C | |
| SCHEMBL14397205 | 0.68 | ALDH1A1 (0.42) | NTRK1GAAPTGS2KDM4ELMNA | |
| SCHEMBL14397210 | 0.67 | GAA (0.45) | NTRK1GAAKMT2AMEN1L3MBTL1 | |
| SCHEMBL11901256 | 0.65 | NOD2 (0.56) | NOD2NOD1PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015088564-A1 | P2X4 RECEPTOR MODULATING COMPOUNDS | SUNOVION PHARMACEUTICALS INC. (US) | 2015-06-18 | — | — | WO | disclosed |
| WO-2015088564-A1 | P2X4 RECEPTOR MODULATING COMPOUNDS | SUNOVION PHARMACEUTICALS INC. (US) | 2015-06-18 | — | — | WO | disclosed |