Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.51 |
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.51 |
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.51 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16795119 | 0.81 | L3MBTL1 (0.46) | L3MBTL1BRD4ALDH1A1KDM4E | |
| SCHEMBL16795141 | 0.79 | CXCR3 (0.51) | L3MBTL1 | |
| SCHEMBL16795223 | 0.74 | SIGMAR1 (0.56) | — | |
| SCHEMBL16795410 | 0.74 | L3MBTL3 (0.42) | L3MBTL1L3MBTL3MBTD1TP53BP1BRD4 | |
| SCHEMBL13990656 | 0.73 | L3MBTL3 (0.68) | L3MBTL1L3MBTL3MBTD1TP53BP1RECQL | |
| SCHEMBL6212951 | 0.72 | L3MBTL3 (0.66) | L3MBTL1L3MBTL3MBTD1TP53BP1RECQL | |
| SCHEMBL14981031 | 0.72 | L3MBTL1 (0.58) | L3MBTL1HRH3ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL28690097 | 0.71 | L3MBTL3 (0.64) | L3MBTL1L3MBTL3MBTD1TP53BP1RECQL | |
| SCHEMBL10264415 | 0.71 | L3MBTL3 (0.65) | L3MBTL1L3MBTL3MBTD1TP53BP1HRH3 | |
| SCHEMBL15759135 | 0.71 | L3MBTL3 (0.65) | L3MBTL1L3MBTL3MBTD1TP53BP1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015086693-A1 | PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2015-06-18 | — | — | WO | disclosed |