Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.56 |
| ▸ | NCF1 | P14598 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 5/20 | 0.49 |
| ▸ | HTR3A | P46098 | 4/20 | 0.49 |
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR5A | P47898 | 2/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1442314 | 0.94 | HTR6 (0.63) | HTR6ADRB1NCF1HTR1AHTR3A | |
| SCHEMBL2782013 | 0.87 | LMNA (0.51) | HTR6ADRB1HTR1AHTR2ACYP2D6 | |
| SCHEMBL1413377 | 0.85 | HTT (0.54) | HTR6ADRB1HTR2ACYP2D6KDM4E | |
| Hydrochloric Acid SCHEMBL11852231 | 0.83 | JAK2 (0.55) | HTR6HTR1AHTR2ACYP2D6HSD17B10 | |
| SCHEMBL6407264 | 0.83 | LMNA (0.51) | HTR6ADRB1HTR1ACYP2D6TSHR | |
| SCHEMBL3416625 | 0.77 | HTR1A (0.59) | HTR6ADRB1HTR1AHTR3AHTR7 | |
| SCHEMBL7548171 | 0.76 | BCHE (0.44) | HTR6ADRB1HTR1AHTR2ACYP2D6 | |
| SCHEMBL1413397 | 0.76 | HTR6 (0.56) | HTR6HTR1AHTR7HTR2AHSD17B10 | |
| SCHEMBL1413396 | 0.76 | ALDH1A1 (0.55) | NCF1CYP1A2CYP2D6KDM4EALDH1A1 | |
| SCHEMBL21047718 | 0.74 | BCHE (0.42) | HTR6ADRB1HTR1ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015082499-A2 | PHARMACEUTICAL COMPOUND | IOMET PHARMA LTD (GB) | 2015-06-11 | — | — | WO | disclosed |