Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16803275 | 0.78 | MEN1 (0.55) | POLBABCB1ABCC1USP2SMN1; SMN2 | |
| SCHEMBL1270959 | 0.71 | RXFP1 (0.50) | SMN1; SMN2RAB9ATP53KMT2AHPGD | |
| SCHEMBL1225985 | 0.71 | GDA (0.36) | SMN1; SMN2RAB9ALMNA | |
| SCHEMBL16675191 | 0.70 | POLB (0.74) | POLBABCB1ABCC1USP2SMN1; SMN2 | |
| SCHEMBL24728145 | 0.69 | SYK (0.60) | POLBMAPK1 | |
| SCHEMBL12894751 | 0.69 | ALDH1A1 (0.32) | SMN1; SMN2MAPTMEN1KMT2ALMNA | |
| SCHEMBL4494426 | 0.69 | HDAC6 (0.61) | ABCB1ABCC1 | |
| SCHEMBL16675167 | 0.68 | ABCB1 (0.68) | POLBABCB1SMN1; SMN2MAPTTP53 | |
| SCHEMBL16675161 | 0.68 | ABCB1 (0.68) | POLBABCB1SMN1; SMN2MAPTTP53 | |
| SCHEMBL1224554 | 0.68 | ROCK2 (0.54) | RAB9AMAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602478-B1 | Novel process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives | HOFFMANN LA ROCHE (CH) | 1996-07-31 | — | — | EP | disclosed |
| EP-0602478-A1 | Novel process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-22 | — | — | EP | disclosed |