SCHEMBL1680786

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31546284	0.87	FBP1 (0.54)	FBP1PDCD1CD274GRIN2DGRIN3B
	SCHEMBL28302510	0.82	ALDH1A1 (0.55)	FBP1PDCD1CD274GRIN2DGRIN3B
	SCHEMBL6981746	0.82	AKR1C3 (0.59)	FBP1PDCD1CD274GRIN2DGRIN3B
	Balazipone SCHEMBL636109	0.82	PDCD1 (0.55)	FBP1PDCD1CD274GRIN2DGRIN3B
	SCHEMBL5970912	0.82	PDCD1 (0.51)	FBP1PDCD1CD274GRIN2DGRIN3B
	SCHEMBL3115027	0.82	AKR1C3 (0.59)	FBP1PDCD1CD274GRIN2DGRIN3B
	SCHEMBL28372992	0.82	AKR1C3 (0.59)	FBP1PDCD1CD274GRIN2DGRIN3B
	SCHEMBL5970541	0.82	ALDH1A1 (0.55)	FBP1PDCD1CD274GRIN2DGRIN3B
	SCHEMBL1554030	0.81	SLC9A1 (0.48)	FBP1
	SCHEMBL6492531	0.81	FBP1 (0.55)	FBP1PDCD1CD274GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.