SCHEMBL1680992

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1681262	0.90	FFAR1 (0.57)	MMP13PLK1LOXLOXL2ROCK2
	SCHEMBL13491527	0.89	MMP13 (0.61)	MMP13KMT2AROCK2CYP3A4CYP2D6
	SCHEMBL13491492	0.89	MMP13 (0.53)	MMP13PLK1ROCK2CYP3A4CYP2D6
	SCHEMBL13491676	0.88	MMP13 (0.64)	MMP13PLK1ROCK2CYP3A4CYP2D6
	SCHEMBL1681075	0.88	MMP13 (0.61)	MMP13KMT2AROCK2CYP3A4CYP2D6
	SCHEMBL1681116	0.87	ALOX15 (0.58)	MMP13PLK1ROCK2CYP3A4CYP2D6
	SCHEMBL1680887	0.87	EGLN1 (0.56)	MMP13PLK1ROCK2CYP3A4CYP2D6
	SCHEMBL1680767	0.86	SCN9A (0.50)	MMP13PLK1LOXLOXL2ROCK2
	SCHEMBL1680867	0.86	EGLN1 (0.55)	MMP13PLK1CYP3A4EGLN1HTT
	SCHEMBL13002987	0.85	ROCK2 (0.65)	MMP13PLK1KMT2AROCK2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.