Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ACACA | Q13085 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730297 | 0.82 | MEN1 (0.57) | MEN1KMT2AACACAALOX15ADORA3 | |
| SCHEMBL15358870 | 0.78 | KDM4E (0.47) | MEN1KMT2AACACAADORA3ALDH1A1 | |
| SCHEMBL29558419 | 0.77 | TOP1 (0.61) | MEN1KMT2AALOX15 | |
| SCHEMBL3794157 | 0.77 | TOP1 (0.61) | MEN1KMT2AALOX15 | |
| SCHEMBL15349956 | 0.76 | MMP3 (0.45) | MEN1KMT2APTPN1ALDH1A1MAPT | |
| SCHEMBL422442 | 0.75 | ALOX15 (0.76) | MEN1KMT2AACACAALOX15PPARG | |
| SCHEMBL9587290 | 0.74 | MEN1 (0.57) | MEN1KMT2AACACAALOX15SMN1; SMN2 | |
| SCHEMBL28414196 | 0.72 | ACACA (0.65) | MEN1KMT2AACACAALOX15PTPN1 | |
| SCHEMBL8473209 | 0.72 | PTPN1 (0.55) | MEN1KMT2AACACAALOX15PTPN1 | |
| SCHEMBL8175663 | 0.71 | PTPN1 (0.54) | ACACAALOX15PTPN1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9839690-B2 | Singlet oxygen-labile linkers and methods of production and use thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2017-12-12 | — | — | US | disclosed |
| US-20170014510-A1 | Singlet Oxygen-Labile Linkers and Methods of Production and Use Thereof | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2017-01-19 | — | — | US | disclosed |
| US-9393306-B2 | Singlet oxygen-labile linkers and methods of production and use thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2016-07-19 | — | — | US | disclosed |
| US-20150165026-A1 | SINGLET OXYGEN-LABILE LINKERS AND METHODS OF PRODUCTION AND USE THEREOF | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2015-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170014510-A1 | Singlet Oxygen-Labile Linkers and Methods of Production and Use Thereof | PPOX, DUOX1, PAICS | MEN1 2293/4885KMT2A 2599/4885ACACA 2788/4885 |
| US-20150165026-A1 | SINGLET OXYGEN-LABILE LINKERS AND METHODS OF PRODUCTION AND USE THEREOF | PPOX, DUOX1, PAICS | MEN1 2293/4885KMT2A 2599/4885ACACA 2788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.