SCHEMBL1682017

SCHEMBL1682017

C=CC(c1ccccc1)S(=O)(=O)[O-].[Na+]

nearest known ligand 0.35

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 known ✓ O43570 3/20 0.35
CA2 known ✓ P00918 3/20 0.35
CA1 known ✓ P00915 1/20 0.33
CA9 Q16790 3/20 0.35
CYP2C19 P33261 2/20 0.35
PTPN1 P18031 1/20 0.35
KDM4E B2RXH2 3/20 0.35
MAPT P10636 3/20 0.35
CYP3A4 P08684 2/20 0.35
ALOX15 P16050 2/20 0.35
SRC P12931 2/20 0.34
HPGD P15428 2/20 0.34
LMNA P02545 2/20 0.34
USP2 O75604 1/20 0.34
TP53 P04637 1/20 0.34
ALOX12 P18054 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALDH1A1 P00352 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium Ion SCHEMBL3294055 0.96 CYP2C19 (0.35) CA12CA2CA9CYP2C19PTPN1
SCHEMBL776436 0.81 CYP2C19 (0.38) CYP2C19KDM4EMAPTCYP3A4ALOX15
SCHEMBL9234234 0.79 CYP2C19 (0.37) CYP2C19KDM4EMAPTCYP3A4ALOX15
SCHEMBL1172421 0.79 CYP2C19 (0.37) CYP2C19KDM4EMAPTCYP3A4ALOX15
SCHEMBL11497012 0.78 CYP2C19 (0.36) CYP2C19KDM4EMAPTCYP3A4ALOX15
SCHEMBL88528 0.78 SRC (0.48) CYP2C19KDM4EMAPTCYP3A4ALOX15
SCHEMBL7166967 0.78 CA1 (0.38) CA12CA2CA9CYP2C19KDM4E
SCHEMBL1173054 0.78 HSD17B10 (0.38) CYP2C19KDM4EMAPTCYP3A4ALOX15
SCHEMBL10889949 0.76 SRC (0.47) CYP2C19KDM4EMAPTCYP3A4ALOX15
Ammonia Solution, Strong SCHEMBL9066051 0.76 SRC (0.47) CYP2C19KDM4EMAPTCYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0566028-B1 Gelable compositions of water soluble polymers PHILLIPS PETROLEUM CO (US) 1996-05-22 EP claimed
EP-0475325-B1 Gelatin of acrylamide-containing polymers with aminobenzoic acid compounds and water dispersible aldehydes PHILLIPS PETROLEUM CO (US) 1995-04-19 EP claimed
US-5399269-A Enhanced oil recovery PHILLIPS PETROLEUM COMPANY (US) 1995-03-21 US claimed
EP-0446865-B1 Gelation of acrylamide-containing polymers with hydroxyphenyl alkanols PHILLIPS PETROLEUM CO (US) 1994-09-21 EP claimed
EP-0447967-B1 Gelation of acrylamide-containing polymers with furfuryl alcohol and water dispersible aldehydes PHILLIPS PETROLEUM CO (US) 1994-05-18 EP claimed
EP-0566028-A1 Gelable compositions of water soluble polymers PHILLIPS PETROLEUM COMPANY (US) 1993-10-20 EP claimed
US-5179136-A Enhanced or recovery operations PHILLIPS PETROLEUM COMPANY (US) 1993-01-12 US claimed
US-5100931-A Crosslinking; enhanced oil recovery PHILLIPS PETROLEUM COMPANY (US) 1992-03-31 US claimed
EP-0475325-A1 Gelatin of acrylamide-containing polymers with aminobenzoic acid compounds and water dispersible aldehydes PHILLIPS PETROLEUM COMPANY (US) 1992-03-18 EP claimed
EP-0447967-A2 Gelation of acrylamide-containing polymers with furfuryl alcohol and water dispersible aldehydes PHILLIPS PETROLEUM COMPANY (US) 1991-09-25 EP claimed
EP-0446865-A2 Gelation of acrylamide-containing polymers with hydroxyphenyl alkanols PHILLIPS PETROLEUM COMPANY (US) 1991-09-18 EP claimed
US-5043364-A Adjusting permeability of well bores PHILLIPS PETROLEUM COMPANY (US) 1991-08-27 US claimed
US-4600687-A Photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1986-07-15 US claimed
US-4323644-A ACRYLIC COPOLYMER USEFUL AS A FIXATURE OR GELATIN HARDENING AGENT FUJI PHOTO FILM CO., LTD. (JP) 1982-04-06 US claimed
US-4299748-A DISPERSION OF ACRYLIC COPOLYMERS CONTAINING AN ELECTROCONDUCTIVE COPOLYMER DAICEL LTD. (JP) 1981-11-10 US claimed
JP-57016912-A None JP disclosed
CN-111432891-B Polymer containing phosphonyl-phosphate groups and anionic groups 宝洁公司 2024-01-02 CN disclosed
US-4193795-A FOR DIFFUSION TRANSFER PROCESSES EASTMAN KODAK COMPANY (US) 1980-03-18 US disclosed
US-4168976-A Photographic film units containing aza heterocyclic polymeric mordants EASTMAN KODAK COMPANY (US) 1979-09-25 US disclosed
US-4035317-A VINYL ADDITION POLYMERS AMERICAN CYANAMID COMPANY (US) 1977-07-12 US disclosed