Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9576752 | 0.88 | TSHR (0.38) | HPGDTSHRTHRB | |
| SCHEMBL28187784 | 0.78 | DGAT1 (0.33) | HPGDTSHR | |
| SCHEMBL4065763 | 0.76 | THRB (0.34) | HPGDTSHRTHRB | |
| SCHEMBL16295041 | 0.74 | ALDH1A1 (0.38) | HPGDTSHRTHRB | |
| SCHEMBL4369134 | 0.74 | TSHR (0.38) | HPGDTSHRTHRB | |
| SCHEMBL27985155 | 0.72 | TSHR (0.34) | HPGDTSHR | |
| Acrylic Acid Ethyl Ester SCHEMBL28294928 | 0.71 | TSHR (0.47) | HPGDTSHRTHRB | |
| Acrylic Acid Ethyl Ester SCHEMBL2379184 | 0.70 | TSHR (0.43) | HPGDTSHRTHRB | |
| Acrylic Acid Ethyl Ester SCHEMBL865344 | 0.70 | TSHR (0.40) | HPGDTSHRTHRB | |
| Acrylic Acid Methyl Ester SCHEMBL27656259 | 0.69 | HCAR2 (0.42) | HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680038-B2 | Copolymer containing zwitterionic units and other units, composition comprising the copolymer, and use | RHODIA OPERATIONS (FR) | 2014-03-25 | — | — | US | claimed |
| EP-1966259-B1 | COPOLYMER CONTAINING ZWITTERIONIC UNITS AND OTHER UNITS, COMPOSITION COMPRISING THE COPOLYMER, AND USE | RHODIA OPERATIONS (FR) | 2012-04-18 | — | — | EP | claimed |
| US-20090197791-A1 | COPOLYMER CONTAINING ZWITTERIONIC UNITS AND OTHER UNITS, COMPOSITION COMPRISING THE COPOLYMER, AND USE | RHODIA RECHERCHES ET TECHNOLOGIES (FR) | 2009-08-06 | — | — | US | claimed |
| US-8680038-B2 | Copolymer containing zwitterionic units and other units, composition comprising the copolymer, and use | RHODIA OPERATIONS (FR) | 2014-03-25 | — | — | US | disclosed |
| US-8637622-B2 | Copolymer including betaine units and hydrophobic and/or amphiphilic units, method for preparing same and uses thereof | RHODIA OPERATIONS (FR) | 2014-01-28 | — | — | US | disclosed |
| US-20110092634-A1 | POLYMERIC MICROGEL COMPRISING CATIONIC UNITS | RHODIA OPERATIONS (FR) | 2011-04-21 | — | — | US | disclosed |
| US-20100093874-A1 | COPOLYMER INCLUDING BETAINE UNITS AND HYDROPHOBIC AND/OR AMPHIPHILIC UNITS, METHOD FOR PREPARING SAME AND USES THEREOF | RHODIA OPERATIONS (FR) | 2010-04-15 | — | — | US | disclosed |
| US-20090197791-A1 | COPOLYMER CONTAINING ZWITTERIONIC UNITS AND OTHER UNITS, COMPOSITION COMPRISING THE COPOLYMER, AND USE | RHODIA RECHERCHES ET TECHNOLOGIES (FR) | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093874-A1 | COPOLYMER INCLUDING BETAINE UNITS AND HYDROPHOBIC AND/OR AMPHIPHILIC UNITS, METHOD FOR PREPARING SAME AND USES THEREOF | SLC6A12, BHMT, PHOSPHO1 | HPGD 3443/4885TSHR 4570/4885THRB 2610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.