Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18077856 | 0.86 | ALDH1A1 (0.39) | ALDH1A1FEN1CA1CA2MEN1 | |
| SCHEMBL21028212 | 0.86 | ALDH1A1 (0.39) | ALDH1A1FEN1CA1CA2MEN1 | |
| SCHEMBL16852355 | 0.85 | FFAR4 (0.42) | ALDH1A1FFAR4MEN1ALOX15MAPK1 | |
| SCHEMBL21028344 | 0.85 | ALDH1A1 (0.39) | ALDH1A1FEN1CA1CA2MEN1 | |
| SCHEMBL21028426 | 0.80 | HTT (0.41) | ALDH1A1FEN1CA1CA2LMNA | |
| SCHEMBL16852445 | 0.78 | FLT1 (0.45) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL16852788 | 0.78 | RORC (0.41) | ALDH1A1CA1CA2FFAR4LMNA | |
| SCHEMBL17721214 | 0.75 | CCR2 (0.40) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL16852659 | 0.75 | LMNA (0.41) | FEN1CA1CA2LMNA | |
| SCHEMBL21028211 | 0.74 | RORC (0.41) | ALDH1A1FFAR4MEN1ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150175562-A1 | CARBOXAMIDE OR SULFONAMIDE SUBSTITUTED THIAZOLES AND RELATED DERIVATIVES AS MODULATORS FOR THE ORPHAN NUCLEAR RECEPTOR ROR[GAMMA] | PHENEX PHARMACEUTICALS AG (DE) | 2015-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150175562-A1 | CARBOXAMIDE OR SULFONAMIDE SUBSTITUTED THIAZOLES AND RELATED DERIVATIVES AS MODULATORS FOR THE ORPHAN NUCLEAR RECEPTOR ROR[GAMMA] | RORA, RORB, RORC | ALDH1A1 688/4885FEN1 4845/4885CA1 548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.