SCHEMBL168595

SCHEMBL168595

COc1cc(CC(C(=O)O)C(=O)O)cc(OC)c1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 2/20 0.67
PKM P14618 3/20 0.53
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA3 P07451 1/20 0.53
CA4 P22748 1/20 0.53
CA6 P23280 1/20 0.53
CA5A P35218 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA14 Q9ULX7 1/20 0.53
CA5B Q9Y2D0 1/20 0.53
ALOX5 P09917 3/20 0.51
LMNA P02545 1/20 0.48
GAA P10253 5/20 0.46
KDM4E B2RXH2 3/20 0.46
MAPT P10636 2/20 0.46
PTGS2 P35354 2/20 0.46
PTGS1 P23219 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18821891 0.86 PKM (0.50) LDHAPKMCA12CA1CA2
SCHEMBL20395550 0.86 LDHA (0.50) LDHAPKMCA12CA1CA2
SCHEMBL491220 0.85 LDHA (0.67) LDHAKDM4EMAPTPTGS2ALDH1A1
SCHEMBL491022 0.83 LDHA (0.47) LDHAPKMCA12CA1CA2
SCHEMBL20162238 0.82 LDHA (0.50) LDHAKDM4ETSHRKMT2ACYP3A4
SCHEMBL20162267 0.82 LDHA (0.46) LDHAPKMCA12CA1CA2
SCHEMBL491190 0.81 LDHA (0.76) LDHAALOX5LMNAGAAPTGS1
SCHEMBL9654228 0.80 LDHA (0.45) LDHAPKMCA12CA1CA2
SCHEMBL490731 0.80 LDHA (1.00) LDHAPKMCA12CA1CA2
SCHEMBL624795 0.79 FOS (0.50) PKMCA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1871735-B1 ANTIOXIDANTS MERCK PATENT GMBH (DE) 2015-12-23 EP claimed
EP-3592329-B1 USE OF COMPATIBLE SOLUTES SUSONITY Commercial GmbH (DE) 2026-02-18 EP disclosed
EP-4007561-B1 PREVENTION AND REDUCTION OF CORNIFICATION DISORDERS AND RELATED COSMETIC AGENTS MERCK PATENT GMBH (DE) 2025-08-27 EP disclosed
EP-4486361-A1 COSMETIC USE OF A COMPOSITION COMPRISING AN AQUEOUS SEAWEED EXTRACT OF PELVETIA CANALICULATA FOR INCREASING GLOSS OF SKIN Merck Patent GmbH (DE) 2025-01-08 EP disclosed
CN-118632702-A Cosmetic use of a composition comprising an extract of carrageen aquatic seaweed for increasing skin shine 默克专利股份有限公司 2024-09-10 CN disclosed
EP-3756642-B1 METHOD TO INCREASE CELLULAR AVAILABILITY OF CALCIUM IN SKIN CELLS AND MIXTURES MERCK PATENT GMBH (DE) 2024-06-26 EP disclosed
EP-4301793-A1 CYANOACRYLATE COMPOSITION WITH HAZARDLESS STABILIZER H.B. Fuller Company (US) 2024-01-10 EP disclosed
WO-2023161415-A1 COSMETIC USE OF A COMPOSITION COMPRISING AN AQUEOUS SEAWEED EXTRACT OF PELVETIA CANALICULATA FOR INCREASING GLOSS OF SKIN MERCK PATENT GMBH (DE) 2023-08-31 WO disclosed
US-11737997-B2 Method to increase cellular availability of calcium in skin cells and mixtures MERCK PATENT GMBH (DE) 2023-08-29 US disclosed
WO-2022187848-A1 CYANOACRYLATE COMPOSITION WITH HAZARDLESS STABILIZER H.B. FULLER COMPANY (US) 2022-09-09 WO disclosed
WO-2008119428-A1 PHOTOSTABLE COMPOSITIONS MERCK PATENT GMBH (DE) 2008-10-09 WO disclosed
WO-2008113450-A2 USE OF CHROMAN-4-ON-DERIVATIVES MERCK PATENT GMBH (DE) 2008-09-25 WO disclosed
WO-2008110465-A1 COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS BASF SE (CH) 2008-09-18 WO disclosed
WO-2008089822-A2 ANTIMICROBIAL COMPOSITION COMPRISING ZINC OXIDE, BARIUM SULPHATE AND SILVER IONS MERCK PATENT GMBH (DE) 2008-07-31 WO disclosed
WO-2008071292-A1 METHOD OF INCREASING THE TANNING EFFECT OF SELF-TANNING SUBSTANCES MERCK PATENT GMBH (DE) 2008-06-19 WO disclosed
WO-2008052631-A1 [(4-OXO-4H-CHROMEN-3-YL)-HYDROXY METHYL]- OR [(4-OXO-4H-CHROMEN-3-YL)-METHYL]-PHOSPHONIC ACID DERIVATES MERCK PATENT GMBH (DE) 2008-05-08 WO disclosed
WO-2008017346-A2 USE OF ASCORBIC ACID DERIVATIVES FOR THE FUNCTIONALIZATION OF MATRICES MERCK PATENT GMBH (DE) 2008-02-14 WO disclosed
WO-2007121818-A1 ANTIOXIDANTS MERCK PATENT GMBH (DE) 2007-11-01 WO disclosed
WO-2007121845-A1 ANTIOXIDANTS MERCK PATENT GMBH (DE) 2007-11-01 WO disclosed
WO-2007118565-A1 USE OF FLAVONOIDS MERCK PATENT GMBH (DE) 2007-10-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11737997-B2 Method to increase cellular availability of calcium in skin cells and mixtures CA2, CHERP, SLC8B1 LDHA 1856/4885PKM 2041/4885CA12 346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.