Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20395550 | 0.85 | LDHA (0.50) | LDHAPKMKDM4EGAAALDH1A1 | |
| SCHEMBL20162240 | 0.85 | CYP2D6 (0.39) | LDHAKDM4EGAAALDH1A1CA12 | |
| SCHEMBL168609 | 0.84 | FOS (0.63) | LDHAGAAALDH1A1ALOX5LMNA | |
| SCHEMBL491022 | 0.83 | LDHA (0.47) | LDHAPKMKDM4EGAAALDH1A1 | |
| SCHEMBL20395656 | 0.82 | SMN1; SMN2 (0.41) | LDHAPKMKDM4EGAAALDH1A1 | |
| SCHEMBL168595 | 0.82 | LDHA (0.67) | LDHAPKMKDM4EGAAALDH1A1 | |
| SCHEMBL934771 | 0.80 | FOS (0.58) | LDHAGAAALDH1A1KMT2AALOX5 | |
| SCHEMBL935389 | 0.78 | HSD17B2 (0.56) | LDHAKDM4EGAAALDH1A1KMT2A | |
| SCHEMBL624795 | 0.76 | FOS (0.50) | PKMKDM4EGAAALDH1A1KMT2A | |
| SCHEMBL18821891 | 0.76 | PKM (0.50) | LDHAPKMKDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| EP-3322400-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | Merck Patent GmbH (DE) | 2018-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | LPO, CAT, GPX4 | LDHA 3865/4885PKM 3502/4885KDM4E 4372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.