Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | KHK | P50053 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30262619 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KEAP1MEN1KMT2AKDM4E | |
| SCHEMBL3574934 | 0.84 | CYP11B1 (0.50) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL404482 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KEAP1MEN1KMT2AKDM4E | |
| SCHEMBL28967099 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KEAP1MEN1KMT2AKDM4E | |
| SCHEMBL5368384 | 0.79 | MAOA (0.44) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL3879887 | 0.79 | TAAR1 (0.55) | MEN1KMT2AKDM4ECYP11B1CYP11B2 | |
| SCHEMBL573864 | 0.78 | MAOB (0.53) | ALDH1A1KDM4ETRPV4MAOAMAOB | |
| SCHEMBL22134762 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KEAP1CYP1A2GAAHTT | |
| SCHEMBL30182222 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KEAP1CYP1A2GAAHTT | |
| SCHEMBL6150149 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KEAP1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 315 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119176746-B | Method for preparing bisphenol A and heterocyclic compound by using waste PC | 浙江大学 | 2025-05-30 | — | — | CN | claimed |
| CN-119176746-A | Method for preparing bisphenol A and heterocyclic compound by using waste PC | 浙江大学 | 2024-12-24 | — | — | CN | claimed |
| CN-118440013-A | Preparation method of quinazoline diketone compound | 安顺学院 | 2024-08-06 | — | — | CN | claimed |
| CN-114380718-B | Acylation method of aniline compound | 河南农业大学 | 2022-09-30 | — | — | CN | claimed |
| CN-114380718-A | Acylation method of aniline compound | 河南农业大学 | 2022-04-22 | — | — | CN | claimed |
| CN-113354558-B | Preparation method of 2-amino-5-fluorobenzonitrile | 无锡双启科技有限公司 | 2022-03-11 | — | — | CN | claimed |
| CN-113354558-A | Preparation method of 2-amino-5-fluorobenzonitrile | 无锡双启科技有限公司 | 2021-09-07 | — | — | CN | claimed |
| CN-108640919-B | Matrine derivative and sophoridine derivative containing aryl amidine or aminoquinoline structure and preparation method thereof | 广西大学 | 2020-09-08 | — | — | CN | claimed |
| CN-117177975-B | Pyrimido [5,4, D ] pyrimidine compounds, compositions comprising the same and uses thereof | 蒙特利尔大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-122055367-A | 5-Oxo-4, 5-dihydroimidazo [1,5-a ] quinazoline compounds as PI3K [ alpha ] inhibitors | 皮卡维森治疗学股份有限公司 | 2026-05-15 | — | — | CN | disclosed |
| EP-4720060-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2026-04-08 | — | — | EP | disclosed |
| US-12509431-B2 | 1,4-dihydroquinazolinone compounds and uses thereof | EDGEWISE THERAPEUTICS, INC. (US) | 2025-12-30 | — | — | US | disclosed |
| US-20250361213-A1 | 1,4-DIHYDROQUINAZOLINONE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS INC (US) | 2025-11-27 | — | — | US | disclosed |
| EP-4594307-A1 | 1,4-DIHYDROQUINAZOLINONE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. (US) | 2025-08-06 | — | — | EP | disclosed |
| EP-1308513-A1 | USE OF POLYPEPTIDE | Takeda Chemical Industries, Ltd. (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1262195-A1 | VASOACTIVE AGENTS | Takeda Chemical Industries, Ltd. (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-6433174-B1 | Process for producing novel naphthyridine derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-08-13 | — | — | US | disclosed |
| EP-1142892-A1 | PROCESSES FOR THE PREPARATION OF NOVEL NAPHTHYRIDINE DERIVATIVES | Nippon Kayaku Kabushiki Kaisha (JP) | 2001-10-10 | — | — | EP | disclosed |
| EP-0519307-A2 | Tetracyclic Imidazodiazepines | F. HOFFMANN-LA ROCHE AG (CH) | 1992-12-23 | — | — | EP | disclosed |
| US-RE28939-E | MUSCLE RELAXANTS, ANALGESICS | SMITHKLINE CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12509431-B2 | 1,4-dihydroquinazolinone compounds and uses thereof | TNNT2, TNNI3, TNNC1 | ALDH1A1 716/4885KEAP1 1991/4885MEN1 3410/4885 |
| US-20250361213-A1 | 1,4-DIHYDROQUINAZOLINONE COMPOUNDS AND USES THEREOF | TNNI3, TNNT2, SDHA | ALDH1A1 780/4885KEAP1 654/4885MEN1 2996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.