Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | KHK | P50053 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12733363 | 0.84 | CYP11B2 (0.54) | ALDH1A1KDM4EMEN1KMT2AMAOA | |
| SCHEMBL168901 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TRPV4KDM4EMEN1KMT2A | |
| SCHEMBL30262619 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TRPV4KDM4EMEN1KMT2A | |
| SCHEMBL573864 | 0.78 | MAOB (0.53) | ALDH1A1TRPV4KDM4EMAOAMAOB | |
| SCHEMBL29137845 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KEAP1GAAHTT | |
| SCHEMBL9327450 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KEAP1GAAHTT | |
| SCHEMBL5070146 | 0.76 | MEN1 (0.48) | ALDH1A1TRPV4KDM4EMEN1KMT2A | |
| SCHEMBL21131569 | 0.76 | TRPV4 (0.45) | ALDH1A1TRPV4KDM4EMEN1KMT2A | |
| SCHEMBL2028221 | 0.76 | KDM4E (0.55) | ALDH1A1TRPV4KDM4EMEN1KMT2A | |
| SCHEMBL57346 | 0.76 | TRPV4 (0.61) | ALDH1A1TRPV4MAOAMAOBCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332789-A | Preparation method of 4-amino-2-fluorobenzamide | 上海康鹏科技股份有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-106946800-A | A kind of synthetic method of (1H, the 3H) diketone of quinazoline 2,4 and its derivative | 华东师范大学 | 2017-07-14 | — | — | CN | claimed |
| US-12528816-B2 | Substituted imidazo [1,2-b] pyridazines and [1, 2, 4] triazolo [ 4,3-b] pyridazines as camkii inhibitors | CARDURION PHARMACEUTICALS, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| EP-4660186-A1 | ACID ADDITION SALT OF 4-AMINO-2-HALOBENZONITRILE COMPOUND AND METHOD FOR PRODUCING SAME | SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2025-12-10 | — | — | EP | disclosed |
| EP-4635568-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA Pharmaceuticals Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| EP-3672954-B1 | COMPOUNDS, SALTS THEREOF AND THEIR USE FOR THE TREATMENT OF DISEASES | ACADIA PHARM INC (US) | 2025-08-13 | — | — | EP | disclosed |
| US-20250197385-A1 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARM INC (US) | 2025-06-19 | — | — | US | disclosed |
| US-20250179072-A1 | TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. | 2025-06-05 | — | — | US | disclosed |
| CN-119768407-A | Protein phosphatase agonist and application thereof | 南京中瑞药业有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-116102495-B | 1,2,3, 4-Tetrahydro-9-aminoacridine compound and application thereof | 浙江工业大学 | 2025-03-21 | — | — | CN | disclosed |
| CN-119331429-A | Azo red dye compound and preparation method and application thereof | 南京晓庄学院 | 2025-01-21 | — | — | CN | disclosed |
| US-5206387-A | Chemical intermediates for memory enhancing drugs | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-04-27 | — | — | US | disclosed |
| US-5189054-A | 3-amidoindolyl derivatives and pharmaceutical compositions thereof | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-02-23 | — | — | US | disclosed |
| US-5112830-A | Cognition Activators | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-05-12 | — | — | US | disclosed |
| EP-0483881-A1 | 3-Amidoindolyl derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1992-05-06 | — | — | EP | disclosed |
| US-5002955-A | Pyrroloquinolines for enhancement of memory | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0371388-A2 | Acridine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |
| US-4843079-A | ALZHEIMER*S DISEASE | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0287977-A2 | Fused heteroalkylene quinolinamines, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-10-26 | — | — | EP | disclosed |
| EP-0268871-A1 | Quinoline derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12528816-B2 | Substituted imidazo [1,2-b] pyridazines and [1, 2, 4] triazolo [ 4,3-b] pyridazines as camkii inhibitors | RYR2, CACNA1C, CAMK4 | ALDH1A1 1793/4885TRPV4 788/4885KDM4E 4364/4885 |
| US-20250179072-A1 | TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS | AKR1C2, AKR1B1, AKR1C1 | ALDH1A1 234/4885TRPV4 3597/4885KDM4E 1460/4885 |
| US-20250197385-A1 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | SLC10A1, CYP27A1, CYP11B2 | ALDH1A1 240/4885TRPV4 3467/4885KDM4E 4595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.