SCHEMBL1689631

SCHEMBL1689631

COC(OC)C1CCNCC1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 14/20 0.36
SLC6A4 P31645 14/20 0.36
SLC6A3 Q01959 13/20 0.36
CPN1 P15169 1/20 0.33
CPB2 Q96IY4 1/20 0.33
HTR2C P28335 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28958068 0.85 SLC6A2 (0.39) SLC6A2SLC6A4SLC6A3
SCHEMBL16070169 0.85 SLC6A2 (0.39) SLC6A2SLC6A4SLC6A3
SCHEMBL20230990 0.85 SLC6A2 (0.39) SLC6A2SLC6A4SLC6A3
SCHEMBL29132357 0.83
SCHEMBL25133345 0.83
SCHEMBL30769428 0.80
SCHEMBL8734417 0.80
SCHEMBL31335115 0.80 CHRM2 (0.35)
SCHEMBL5444117 0.79 SLC6A2 (0.36) SLC6A2SLC6A4SLC6A3CPN1CPB2
SCHEMBL31584249 0.78 DRD2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 444 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617889-B1 Polymers for use as anion exchange membranes ENVISION ENERGY USA LTD. (US) 2026-05-05 US claimed
CN-112661694-B Preparation method of 4- (dimethoxymethyl) -piperidine 西安凯立新材料股份有限公司 2023-04-11 CN claimed
US-20220274955-A1 TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS ARVINAS OPERATIONS, INC. 2022-09-01 US claimed
CN-114085213-B Preparation method of ARV-471 苏州国匡医药科技有限公司 2022-03-25 CN claimed
CN-114085213-A Preparation method of ARV-471 苏州国匡医药科技有限公司 2022-02-25 CN claimed
CN-112661694-A Preparation method of 4- (dimethoxymethyl) -piperidine 西安凯立新材料股份有限公司 2021-04-16 CN claimed
US-20260146044-A1 AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF INCRELAND (CN) 2026-05-28 US disclosed
US-20260144881-A1 HPK1 TARGETING COMPOUNDS AND USES THEREOF ARVINAS OPERATIONS, INC. (US) 2026-05-28 US disclosed
EP-4748840-A1 IMIDAZO[1,2-A]PYRIDINE TYPE IRAK DEGRADATION AGENT AND USE THEREOF TAINUORUI (TIANJIN) BIOTECHNOLOGY CO., LTD (CN) 2026-05-27 EP disclosed
EP-4745142-A1 AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF Increland (CN) 2026-05-20 EP disclosed
CN-122070287-A IRAK 4-targeted degradation agent compound and application thereof 江苏先声药业有限公司 2026-05-19 CN disclosed
CN-116917280-B Tetrahydronaphthalene compound, preparation method thereof and application thereof in medicine 江苏恒瑞医药股份有限公司 2026-05-12 CN disclosed
US-20260125400-A1 TYK2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-05-07 US disclosed
EP-1880996-A1 Spiroindolinepiperidine derivatives Syngenta Limited (GB) 2008-01-23 EP disclosed
US-20060106045-A1 Spiroindolinepiperidine derivatives SYNGENTA PARTICIPATIONS AG (CH) 2006-05-18 US disclosed
EP-1515969-A1 SPIROINDOLINEPIPERIDINE DERIVATIVES Syngenta Limited (GB) 2005-03-23 EP disclosed
WO-2003106457-A1 SPIROINDOLINEPIPERIDINE DERIVATIVES SYNGENTA LIMITED (GB) 2003-12-24 WO disclosed
US-6506901-B2 1-(9H-Carbazol-4-yloxy)-3-((1-(7-trifluoromethyl-quinolin-4-yl) -piperidin-4-lmethyl)-amino)-propan-2-ol, for example; treating diabetes, urinary continence, atherosclerosis, gastrointestinal disorders, glaucoma WYETH 2003-01-14 US disclosed
US-20020037907-A1 Substituted 2- (S) -hydroxy-3- (piperidin-4-yl-methylamino) -propyl ethers and substituted 2-aryl-2- (R) - hydroxy-1- (piperidin-4-yl-methyl) -ethylamine beta-3 adrenergic receptor agonists AMERICAN HOME PRODUCTS CORPORATION (US) 2002-03-28 US disclosed
WO-2002006255-A2 HYDROXY-(PIPERIDIN-4-YL-METHYLAMINO)-ALKYL BETA-3 ADRENERGIC RECEPTOR ANTAGONISTS WYETH (US) 2002-01-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146044-A1 AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF IRAK4, IRAK2, IRAK1 SLC6A2 3829/4885SLC6A4 2666/4885SLC6A3 3402/4885
US-20260125400-A1 TYK2 DEGRADERS AND USES THEREOF TYK2, CSNK2A1, CSNK2A2 SLC6A2 3400/4885SLC6A4 4257/4885SLC6A3 3658/4885
US-20260144881-A1 HPK1 TARGETING COMPOUNDS AND USES THEREOF SGK1, PBK, SGK3 SLC6A2 4152/4885SLC6A4 2996/4885SLC6A3 3265/4885
US-20020037907-A1 Substituted 2- (S) -hydroxy-3- (piperidin-4-yl-methylamino) -propyl ethers and substituted 2-aryl-2- (R) - hydroxy-1- (piperidin-4-yl-methyl) -ethylamine beta-3 adrenergic receptor agonists GPR119, ADRB1, ADRB2 SLC6A2 443/4885SLC6A4 583/4885SLC6A3 417/4885
US-20220274955-A1 TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS MDM2, CRBN, VHL SLC6A2 4566/4885SLC6A4 4229/4885SLC6A3 4209/4885
US-20060106045-A1 Spiroindolinepiperidine derivatives RECQL, OPRD1, NCAPD3 SLC6A2 3045/4885SLC6A4 3459/4885SLC6A3 2661/4885
US-12617889-B1 Polymers for use as anion exchange membranes KCNN3, KCNJ1, KCNH3 SLC6A2 1311/4885SLC6A4 690/4885SLC6A3 350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.