Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16935302 | 0.94 | SIGMAR1 (0.40) | SIGMAR1LMNAHTTRECQLALDH1A1 | |
| SCHEMBL19206327 | 0.86 | METAP2 (0.33) | SIGMAR1DRD2DRD4 | |
| SCHEMBL19206364 | 0.84 | METAP2 (0.33) | SIGMAR1DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL19206340 | 0.84 | METAP2 (0.33) | SIGMAR1DRD2DRD4 | |
| SCHEMBL19206349 | 0.81 | METAP2 (0.31) | — | |
| SCHEMBL19933254 | 0.80 | SIGMAR1 (0.39) | SIGMAR1DRD2DRD4 | |
| SCHEMBL16935382 | 0.79 | VEGFA (0.35) | SIGMAR1CHRM2DRD2DRD4 | |
| SCHEMBL19206351 | 0.78 | — | — | |
| SCHEMBL17346103 | 0.78 | ALDH1A1 (0.45) | LMNAHTTALDH1A1MAPTPKM | |
| SCHEMBL951191 | 0.78 | SIGMAR1 (0.39) | SIGMAR1MAPTCHRM2DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544179-B2 | Organic compounds | GIVAUDAN S.A. (CH) | 2020-01-28 | — | — | US | disclosed |
| US-10544179-B2 | Organic compounds | GIVAUDAN S.A. (CH) | 2020-01-28 | — | — | US | disclosed |
| EP-3097067-B1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2019-07-17 | — | — | EP | disclosed |
| EP-3097067-B1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2019-07-17 | — | — | EP | disclosed |
| US-10196414-B2 | Organic compounds | GIVAUDAN S.A. (CH) | 2019-02-05 | — | — | US | disclosed |
| US-20180066003-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2018-03-08 | — | — | US | disclosed |
| US-20180066003-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2018-03-08 | — | — | US | disclosed |
| EP-3097067-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | Givaudan S.A. (CH) | 2016-11-30 | — | — | EP | disclosed |
| US-20160326199-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN S.A. (CH) | 2016-11-10 | — | — | US | disclosed |
| US-20160326199-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN S.A. (CH) | 2016-11-10 | — | — | US | disclosed |
| WO-2015110515-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2015-07-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160326199-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | PSPH, AS3MT, TST | SIGMAR1 567/4885LMNA 4607/4885HTT 561/4885 |
| US-10196414-B2 | Organic compounds | SOST, TST, MPST | SIGMAR1 341/4885LMNA 4678/4885HTT 1066/4885 |
| US-20180066003-A1 | ORGANIC COMPOUNDS | SOST, TST, MPST | SIGMAR1 341/4885LMNA 4678/4885HTT 1066/4885 |
| US-10544179-B2 | Organic compounds | SOST, TST, MPST | SIGMAR1 341/4885LMNA 4678/4885HTT 1066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.