Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624587 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HPGDLMNASMN1; SMN2CYP2C19 | |
| SCHEMBL19206327 | 0.82 | METAP2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL19206340 | 0.81 | METAP2 (0.33) | — | |
| SCHEMBL19206364 | 0.81 | METAP2 (0.33) | — | |
| SCHEMBL951191 | 0.80 | SIGMAR1 (0.39) | KMT2AMAPTMEN1CYP3A4GAA | |
| Hydrochloric Acid SCHEMBL1465772 | 0.78 | SIGMAR1 (0.38) | SMN1; SMN2KMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL31026596 | 0.78 | SIGMAR1 (0.38) | KMT2AMAPTMEN1CYP3A4GAA | |
| SCHEMBL346711 | 0.78 | TDP1 (0.41) | SMN1; SMN2KMT2AMEN1CYP3A4 | |
| SCHEMBL16935201 | 0.78 | SIGMAR1 (0.38) | ALDH1A1LMNAMAPTHTTPKM | |
| SCHEMBL16935382 | 0.78 | VEGFA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11370736-B2 | Synthesis of fluoro hemiacetals via transition metal-catalyzed fluoro ester and carboxamide hydrogenation | TRIAD NATIONAL SECURITY, LLC (US) | 2022-06-28 | — | — | US | disclosed |
| US-11370736-B2 | Synthesis of fluoro hemiacetals via transition metal-catalyzed fluoro ester and carboxamide hydrogenation | TRIAD NATIONAL SECURITY, LLC (US) | 2022-06-28 | — | — | US | disclosed |
| US-20200308089-A1 | SYNTHESIS OF FLUORO HEMIACETALS VIA TRANSITION METAL-CATALYZED FLUORO ESTER AND CARBOXAMIDE HYDROGENATION | U.S. DEPARTMENT OF ENERGY | 2020-10-01 | — | — | US | disclosed |
| US-20200308089-A1 | SYNTHESIS OF FLUORO HEMIACETALS VIA TRANSITION METAL-CATALYZED FLUORO ESTER AND CARBOXAMIDE HYDROGENATION | U.S. DEPARTMENT OF ENERGY | 2020-10-01 | — | — | US | disclosed |
| US-10550139-B2 | Polydentate ligands and their complexes for molecular catalysis | TRIAD NATIONAL SECURITY, LLC (US) | 2020-02-04 | — | — | US | disclosed |
| US-20170088571-A1 | POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS | TRIAD NATIONAL SECURITY, LLC | 2017-03-30 | — | — | US | disclosed |
| US-20170088571-A1 | POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS | TRIAD NATIONAL SECURITY, LLC | 2017-03-30 | — | — | US | disclosed |
| WO-2015191505-A1 | POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2015-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088571-A1 | POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS | NANS, NCL, NCLN | ALDH1A1 862/4885HPGD 973/4885LMNA 3058/4885 |
| US-10550139-B2 | Polydentate ligands and their complexes for molecular catalysis | NANS, NCL, NCLN | ALDH1A1 862/4885HPGD 973/4885LMNA 3058/4885 |
| US-20200308089-A1 | SYNTHESIS OF FLUORO HEMIACETALS VIA TRANSITION METAL-CATALYZED FLUORO ESTER AND CARBOXAMIDE HYDROGENATION | FH, HIRA, HNF4A | ALDH1A1 1005/4885HPGD 317/4885LMNA 3497/4885 |
| US-11370736-B2 | Synthesis of fluoro hemiacetals via transition metal-catalyzed fluoro ester and carboxamide hydrogenation | FH, HIRA, HNF4A | ALDH1A1 1005/4885HPGD 317/4885LMNA 3497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.