Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.46 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.46 |
| ▸ | P2RY6 known ✓ | Q15077 | 1/20 | 0.46 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.40 |
| ▸ | RAD51 | Q06609 | 10/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | LTA | P01374 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | RAD1 | O60671 | 1/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1695298 | 1.00 | RAD51 (0.62) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL29351268 | 0.86 | RAD1 (0.61) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL19882736 | 0.84 | RAD1 (0.63) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL19154120 | 0.84 | RAD1 (0.63) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL6037155 | 0.84 | RAD1 (0.63) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL6037159 | 0.84 | RAD1 (0.63) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL29384039 | 0.84 | RAD1 (0.63) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL17518462 | 0.84 | RAD1 (0.63) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL2421720 | 0.83 | RAD1 (0.61) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL2421728 | 0.83 | RAD1 (0.61) | RAD51KDM4EUSP2ALDH1A1LTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130130399-A1 | CO2 Indicator | UNIVERSITY OF STRATHCLYDE (GB) | 2013-05-23 | — | — | US | claimed |
| EP-2591335-A1 | CO2 INDICATOR | University of Strathclyde (GB) | 2013-05-15 | — | — | EP | claimed |
| WO-2011141707-A1 | CO2 INDICATOR | UNIVERSITY OF STRATHCLYDE (GB) | 2011-11-17 | — | — | WO | claimed |
| US-20130130399-A1 | CO2 Indicator | UNIVERSITY OF STRATHCLYDE (GB) | 2013-05-23 | — | — | US | disclosed |
| EP-2591335-A1 | CO2 INDICATOR | University of Strathclyde (GB) | 2013-05-15 | — | — | EP | disclosed |
| WO-2011141707-A1 | CO2 INDICATOR | UNIVERSITY OF STRATHCLYDE (GB) | 2011-11-17 | — | — | WO | disclosed |
| US-8026021-B2 | Film forming material and preparation of surface relief and optically anisotropic structures by irradiating a film of the said material | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2011-09-27 | — | — | US | disclosed |
| WO-2009087046-A1 | HAND WASHING ASSESSMENT METHOD | UNILEVER PLC (GB) | 2009-07-16 | — | — | WO | disclosed |
| US-20090001632-A1 | Film Forming Material and Preparation of Surface Relief and Optically Anisotropic Structures by Irradiating a Film of the Said Material | FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2009-01-01 | — | — | US | disclosed |
| EP-1794236-B1 | FILM FORMING MATERIAL AND PREPARATION OF SURFACE RELIEF AND OPTICALLY ANISOTROPIC STRUCTURES BY IRRADIATING A FILM OF THE SAID MATERIAL | FRAUNHOFER GES FORSCHUNG (DE) | 2008-12-31 | — | — | EP | disclosed |
| EP-1794236-A1 | FILM FORMING MATERIAL AND PREPARATION OF SURFACE RELIEF AND OPTICALLY ANISOTROPIC STRUCTURES BY IRRADIATING A FILM OF THE SAID MATERIAL | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006024500-A1 | FILM FORMING MATERIAL AND PREPARATION OF SURFACE RELIEF AND OPTICALLY ANISOTROPIC STRUCTURES BY IRRADIATING A FILM OF THE SAID MATERIAL | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2006-03-09 | — | — | WO | disclosed |
| EP-1632520-A1 | Film forming material and preparation of surface relief and optically anisotropic structures by irradiating a film of the said material | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2006-03-08 | — | — | EP | disclosed |