SCHEMBL16973305

SCHEMBL16973305

Cc1c(C(=O)N(C)c2ccnnc2)cnn1C(C)C1(C#N)CC1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ NPC1 O15118 1/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20788678 0.90 KMT2A (0.35) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL15474207 0.87 OXTR (0.38) —
SCHEMBL20210961 0.84 OXTR (0.31) —
SCHEMBL20788679 0.83 KMT2A (0.35) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL16973453 0.81 KMT2A (0.41) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL16973433 0.80 KMT2A (0.40) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL19768896 0.79 KMT2A (0.38) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL20788688 0.78 OXTR (0.37) —
SCHEMBL16973435 0.78 KMT2A (0.38) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL16973298 0.77 KMT2A (0.38) KMT2AMEN1NPC1RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 432 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI INDUSTRIES LTD. (IN) 2024-07-11 — — US claimed
EP-4346412-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI Industries Ltd. (IN) 2024-04-10 — — EP claimed
CN-117396074-A Fungicidal compositions containing oxadiazole compounds PI工业有限公司 2024-01-12 — — CN claimed
US-11839214-B2 Fungicidal mixture comprising substituted pyridines BASF SE (DE) 2023-12-12 — — US claimed
CN-116076518-A Pyrimidinium compounds and mixtures thereof for combating animal pests 巴斯夫欧洲公司 2023-05-09 — — CN claimed
WO-2022249074-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI INDUSTRIES LTD. (IN) 2022-12-01 — — WO claimed
EP-3978504-A1 CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDINE DERIVATIVES FOR COMBATING ANIMAL PESTS BASF SE (DE) 2022-04-06 — — EP claimed
US-20220046925-A1 METHOD OF CONTROLLING PESTS BY SEED TREATMENT APPLICATION OF A MESOIONIC COMPOUND OR MIXTURE THEREOF BASF SE (DE) 2022-02-17 — — US claimed
EP-3601298-B1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2021-12-01 — — EP claimed
US-20210355139-A1 Pyrimidinium Compounds and Their Mixtures for Combating Animal Pests BASF SE (DE) 2021-11-18 — — US claimed
EP-3383183-A1 MIXTURES OF CIS-JASMONE ANDBACILLUS AMYLOLIQUEFACIENS BASF SE (DE) 2018-10-10 — — EP claimed
WO-2018177970-A1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2018-10-04 — — WO claimed
WO-2017153200-A1 FUNGICIDAL MIXTURES III COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2017-09-14 — — WO claimed
US-20170238554-A1 Method and Pesticidal Mixtures for Controlling Pentatomidae Pests BASF CORPORATION 2017-08-24 — — US claimed
EP-3206490-A1 METHOD AND PESTICIDAL MIXTURES FOR CONTROLLING PENTATOMIDAE PESTS BASF SE (DE) 2017-08-23 — — EP claimed
WO-2017137351-A1 MIXTURES AND COMPOSITIONS COMPRISING PAENIBACILLUS STRAINS OR FUSARICIDINS AND CHEMICAL PESTICIDES BASF SE (DE) 2017-08-17 — — WO claimed
EP-3205208-A1 MIXTURES AND COMPOSITIONS COMPRISING PAENIBACILLUS STRAINS OR FUSARICIDINS AND CHEMICAL PESTICIDES BASF SE (DE) 2017-08-16 — — EP claimed
WO-2017093163-A1 MIXTURES OF CIS-JASMONE AND BACILLUS AMYLOLIQUEFACIENS BASF SE (DE) 2017-06-08 — — WO claimed
EP-3111763-A1 PESTICIDAL COMPOSITIONS COMPRISING A TRIAZOLE COMPOUND BASF Agro B.V. (NL) 2017-01-04 — — EP claimed
WO-2016059240-A1 METHOD AND PESTICIDAL MIXTURES FOR CONTROLLING PENTATOMIDAE PESTS BASF SE (DE) 2016-04-21 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839214-B2 Fungicidal mixture comprising substituted pyridines ME1, DPM1, TH KMT2A 2611/4885MEN1 1988/4885NPC1 3390/4885
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS OXA1L, NOX1, NOX3 KMT2A 3280/4885MEN1 2968/4885NPC1 2904/4885
US-20220046925-A1 METHOD OF CONTROLLING PESTS BY SEED TREATMENT APPLICATION OF A MESOIONIC COMPOUND OR MIXTURE THEREOF MANBA, CMA1, MTX1 KMT2A 2080/4885MEN1 157/4885NPC1 2502/4885
US-20210355139-A1 Pyrimidinium Compounds and Their Mixtures for Combating Animal Pests THOP1, NIT2, DDT KMT2A 3738/4885MEN1 1895/4885NPC1 2964/4885
US-20170238554-A1 Method and Pesticidal Mixtures for Controlling Pentatomidae Pests CASP9, CASP6, CASP14 KMT2A 3269/4885MEN1 1446/4885NPC1 4433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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