Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16975556 | 0.83 | ALDH1A1 (0.32) | — | |
| SCHEMBL16985342 | 0.82 | GRIA1 (0.37) | GRIA1GRIA2GRIA3GRIA4TDP1 | |
| SCHEMBL18383145 | 0.76 | POLB (0.43) | MAPTKMT2A | |
| SCHEMBL16985359 | 0.75 | CYP4F2 (0.39) | GRIA1GRIA2GRIA3GRIA4KMT2A | |
| SCHEMBL29078400 | 0.69 | GRIA1 (0.39) | GRIA1GRIA2GRIA3GRIA4SIRT3 | |
| SCHEMBL23745310 | 0.69 | — | — | |
| SCHEMBL24907460 | 0.69 | — | — | |
| SCHEMBL25019043 | 0.67 | LRRK2 (0.43) | — | |
| SCHEMBL12837966 | 0.65 | NOS1 (0.44) | — | |
| SCHEMBL17382010 | 0.65 | LMNA (0.41) | GRIA1GRIA2GRIA3GRIA4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015113452-A1 | COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2015-08-06 | — | — | WO | disclosed |