SCHEMBL1699417

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10271797	0.79	CRHR1 (0.42)	CRHR1KDM4EMAPK1DPP4GUSB
	SCHEMBL31277250	0.79	LMNA (0.52)	LMNAHTTCYP1A2HIF1AHSD17B10
	SCHEMBL3262903	0.79	LMNA (0.52)	LMNAHTTCYP1A2HIF1AHSD17B10
	SCHEMBL9618848	0.78	LMNA (0.50)	LMNAHTTCYP2C19CYP1A2CYP2D6
	SCHEMBL10271796	0.78	GPR84 (0.40)	CRHR1KDM4EMAPK1DPP4GUSB
	SCHEMBL30535784	0.76	PTGS1 (0.46)	KDM4ELMNAHTTGPR84CYP1A2
	SCHEMBL31318250	0.75	CYP1A2 (0.52)	KDM4ELMNAHTTGPR84CYP1A2
	SCHEMBL14413583	0.73	LMNA (0.50)	KDM4ELMNAHTTCYP1A2HSD17B10
	SCHEMBL10272100	0.72	CRHR1 (0.36)	CRHR1KDM4EMAPK1DPP4GPR84
	SCHEMBL1699322	0.72	LMNA (0.48)	LMNAHTTCYP2C19CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.