SCHEMBL1699736

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1699415	0.90	PTGDR2 (0.41)	PTPN11KDM4EALOX15PTGDR2MAPT
	SCHEMBL1699300	0.85	CYP3A4 (0.39)	PTPN11KDM4EPOLBGAACYP19A1
	SCHEMBL1699377	0.85	PTPN11 (0.37)	PTPN11KDM4EALOX15PPARGPPARA
	SCHEMBL1699312	0.84	ALOX15 (0.39)	PTPN11ALOX15MEN1KMT2AGABRA2
	SCHEMBL1699400	0.83	KDM4E (0.41)	PTPN11KDM4EPOLBGAACYP19A1
	SCHEMBL1699478	0.79	CCR2 (0.39)	POLBALOX15MEN1KMT2AGABRA2
	SCHEMBL1699600	0.77	MEN1 (0.40)	ALOX15MEN1MAPTCNR1CNR2
	SCHEMBL1699428	0.76	MAPT (0.39)	KDM4EPOLBMEN1MAPTKMT2A
	SCHEMBL1699544	0.76	CYP3A4 (0.48)	KDM4ECYP19A1MEN1CYP1A2CYP3A4
	SCHEMBL15165174	0.76	CYP3A4 (0.40)	KDM4EPOLBGAAALOX15CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.