Glyphosate

Glyphosate

SCHEMBL1701849

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nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BBOX1 O75936 4/20 0.32
FFAR3 O14843 2/20 0.32
HDAC3 O15379 2/20 0.32
HDAC1 Q13547 2/20 0.32
HDAC2 Q92769 2/20 0.32
HDAC8 Q9BY41 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glyphosate SCHEMBL9947944 0.84 CA4 (0.35)
Glyphosate SCHEMBL3394676 0.84 CA4 (0.35)
Glyphosate SCHEMBL18414 0.84 CA12 (0.37)
Glyphosate SCHEMBL18450 0.84 CA4 (0.39) FFAR3HDAC3HDAC1HDAC2HDAC8
Glyphosate SCHEMBL7194092 0.84 CA4 (0.35)
Glyphosate SCHEMBL3395373 0.84 CA4 (0.35)
Glyphosate SCHEMBL9756253 0.84 CA4 (0.35)
Glyphosate SCHEMBL3665222 0.84 FOLH1 (0.38)
Tetrabuthylammonium SCHEMBL1702368 0.83 SLC22A1 (0.39)
Glyphosate SCHEMBL1401794 0.82 FOLH1 (0.32) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140309419-A1 METHOD FOR ENHANCING THE THERMAL STABILITY OF IONIC COMPOUNDS Danmarks Tekniske Universite (DK) 2014-10-16 US disclosed
EP-2750661-A1 METHOD FOR ENHANCING THE THERMAL STABILITY OF IONIC COMPOUNDS Danmarks Tekniske Universitet (DK) 2014-07-09 EP disclosed
US-20130203602-A1 SUPPORTED BIOLOGICALLY ACTIVE COMPOUNDS DANMARKS TEKNISKE UNIVERSITET (DK) 2013-08-08 US disclosed
US-20130109572-A1 HERBICIDAL COMPOSITIONS AND METHODS OF USE THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2013-05-02 US disclosed
WO-2013030299-A1 METHOD FOR ENHANCING THE THERMAL STABILITY OF IONIC COMPOUNDS DANMARKS TEKNISKE UNIVERSITET (DK) 2013-03-07 WO disclosed
EP-2544664-A1 SUPPORTED BIOLOGICALLY ACTIVE COMPOUNDS Danmarks Tekniske Universitet (DK) 2013-01-16 EP disclosed
WO-2012006313-A2 HERBICIDAL COMPOSITIONS AND METHODS OF USE THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2012-01-12 WO disclosed
WO-2011110662-A1 SUPPORTED BIOLOGICALLY ACTIVE COMPOUNDS DANMARKS TEKNISKE UNIVERSITET (DK) 2011-09-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130109572-A1 HERBICIDAL COMPOSITIONS AND METHODS OF USE DDT, ACHE, CAT BBOX1 667/4885FFAR3 1695/4885HDAC3 1438/4885
US-20130203602-A1 SUPPORTED BIOLOGICALLY ACTIVE COMPOUNDS MIF, BMP2, BMP4 BBOX1 1131/4885FFAR3 4635/4885HDAC3 1784/4885
US-20140309419-A1 METHOD FOR ENHANCING THE THERMAL STABILITY OF IONIC COMPOUNDS NUP50, NUP188, CTCF BBOX1 4793/4885FFAR3 4788/4885HDAC3 1218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.