Glyphosate

Glyphosate

SCHEMBL3394676

O=C([O-])CNCP(=O)([O-])[O-].O=C([O-])CNCP(=O)([O-])[O-].[Ca+2].[Ca+2].[Ca+2]

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Glyphosate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA4 P22748 2/20 0.35
FOLH1 Q04609 3/20 0.34
LMNA P02545 2/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glyphosate SCHEMBL18414 0.95 CA12 (0.37) CA4FOLH1LMNACA12CA1
Glyphosate SCHEMBL9756253 0.95 CA4 (0.35) CA4FOLH1LMNACA12CA1
Glyphosate SCHEMBL3395373 0.95 CA4 (0.35) CA4FOLH1LMNACA12CA1
Glyphosate SCHEMBL3665222 0.95 FOLH1 (0.38) CA4FOLH1LMNACA12CA1
Glyphosate SCHEMBL7194092 0.95 CA4 (0.35) CA4FOLH1LMNACA12CA1
Glyphosate SCHEMBL9947944 0.95 CA4 (0.35) CA4FOLH1LMNACA12CA1
Glyphosate SCHEMBL18450 0.95 CA4 (0.39) CA4FOLH1LMNACA12CA1
Glyphosate SCHEMBL3294894 0.93 CA12 (0.35) CA4FOLH1LMNACA12CA1
Glyphosate SCHEMBL1401794 0.89 FOLH1 (0.32) CA4FOLH1
Glyphosate SCHEMBL1701849 0.84 BBOX1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117463249-A Method for recycling glyphosate from glyphosate mother liquor 安徽捷胜生物科技股份有限公司 2024-01-30 CN claimed
CN-117463249-A Method for recycling glyphosate from glyphosate mother liquor 安徽捷胜生物科技股份有限公司 2024-01-30 CN disclosed
CN-117463249-A Method for recycling glyphosate from glyphosate mother liquor 安徽捷胜生物科技股份有限公司 2024-01-30 CN disclosed
CN-219290689-U Be used for glyphosate ammonium salt precipitation device 山东奥联生物科技有限公司 2023-07-04 CN disclosed
CN-219290689-U Be used for glyphosate ammonium salt precipitation device 山东奥联生物科技有限公司 2023-07-04 CN disclosed
CN-115321736-A Treatment method of glyphosate production wastewater and high-value recycling of phosphorus-containing waste 中国科学院过程工程研究所 2022-11-11 CN disclosed
EP-2172107-A2 Process for the preparation of a dry pesticidal composition containing a dicarboxylate component Monsanto Technology LLC (US) 2010-04-07 EP disclosed
CN-101565177-A Method for synchronously reclaiming orthophosphorous acid and glyphosate in glyphosate production wastewater by chemical precipitation method UNIV NANJING NORMAL (CN) 2009-10-28 CN disclosed
US-7141532-B2 Process for the preparation of a dry pesticidal composition containing a dicarboxylate component MONSANTO TECHNOLOGY LLC (US) 2006-11-28 US disclosed
EP-1538910-A2 PROCESS FOR THE PREPARATION OF A DRY PESTICIDAL COMPOSITION CONTAINING A DICARBOXYLATE COMPONENT Monsanto Technology LLC (US) 2005-06-15 EP disclosed
US-6831041-B2 Based on 2-(1-(2-(4-chlorophenoxy)propoxyimino)butyl)-3-hydroxy-5 -(tetrahydrothiopyran-3-yl)cyclohex-2-enone lithium salt; containing dicarboxylic ester with anionic and nonionic surfactants; stability; rice herbicides BASF AKTIENGESELLSCHAFT (DE) 2004-12-14 US disclosed
US-20040097374-A1 Oil suspension concentrates based on a cyclohexenone oxime ether lithium salt and the use thereof as plant protection agents BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed
US-20040077499-A1 Process for the preparation of a dry pesticidal composition containing a dicarboxylate component MONSANTO TECHNOLOGY LLC 2004-04-22 US disclosed
WO-2004019684-A2 PROCESS FOR THE PREPARATION OF A DRY PESTICIDAL COMPOSITION CONTAINING A DICARBODYLATE COMPONENT MONSANTO TECHNOLOGY LLC (US) 2004-03-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040097374-A1 Oil suspension concentrates based on a cyclohexenone oxime ether lithium salt and the use thereof as plant protection agents OXSR1, SCD, PAOX CA4 2473/4885FOLH1 4379/4885LMNA 1498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.