Glyphosate

Glyphosate

SCHEMBL18414

O=C([O-])CNCP(=O)([O-])[O-].[K+].[K+].[K+]

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA

The experimentally established mechanism targets of Glyphosate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
CA4 P22748 2/20 0.35
FOLH1 Q04609 3/20 0.34
LMNA P02545 2/20 0.33
SLC34A1 Q06495 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glyphosate SCHEMBL3294894 0.98 CA12 (0.35) CA12CA1CA2CA9CA4
Glyphosate SCHEMBL3395373 0.95 CA4 (0.35) CA12CA1CA2CA9CA4
Glyphosate SCHEMBL3394676 0.95 CA4 (0.35) CA12CA1CA2CA9CA4
Glyphosate SCHEMBL9756253 0.95 CA4 (0.35) CA12CA1CA2CA9CA4
Glyphosate SCHEMBL3665222 0.95 FOLH1 (0.38) CA12CA1CA2CA9CA4
Glyphosate SCHEMBL9947944 0.95 CA4 (0.35) CA12CA1CA2CA9CA4
Glyphosate SCHEMBL7194092 0.95 CA4 (0.35) CA12CA1CA2CA9CA4
Glyphosate SCHEMBL18450 0.95 CA4 (0.39) CA12CA1CA2CA9CA4
Glyphosate SCHEMBL1401794 0.89 FOLH1 (0.32) CA4FOLH1
Glyphosate SCHEMBL5087546 0.87 FFAR3 (0.35) CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4221 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260060251-A1 HERBICIDAL AGENT COMPOSITION AND WEED CONTROL METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2026-03-05 US claimed
US-20260060254-A1 HERBICIDAL COMPOSITIONS BAYER AG (DE) 2026-03-05 US claimed
US-20250359550-A1 METHOD FOR WEED CONTROL IN LAWN OR TURF DISCOVERY PURCHASER CORPORATION (US) 2025-11-27 US claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-4651712-A1 ADJUVANT COMPOSITION, IN PARTICULAR FOR AGROCHEMICALS, METHOD FOR MANUFACTURE AND USE THEREOF SN BIOTECH TECHNOLOGIES SPÓLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA SPOLKA KOMANDYTOWA (PL) 2025-11-26 EP claimed
US-12458027-B2 Glyphosate composition for dicamba tank mixtures with improved volatility MONSANTO TECHNOLOGY LLC (US) 2025-11-04 US claimed
US-12453347-B2 Pesticide emulsion concentrates containing natural or petroleum derived oils and methods of use CORTEVA AGRISCIENCE LLC (US) 2025-10-28 US claimed
US-12453351-B2 Herbicide compatibility improvement MONSANTO TECHNOLOGY LLC (US) 2025-10-28 US claimed
US-20250318528-A1 HERBICIDE COMPOSITION AND WEED CONTROLLING METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-10-16 US claimed
EP-4429460-B1 SURFACTANT COMBINATION FOR AQUEOUS AGROCHEMICAL (CROP PROTECTION) SUSPENSION FORMULATIONS WITH HIGH SALT CONTENT AND LOW-CONCENTRATION OF SULFONYLUREA HERBICIDE BAYER AG (DE) 2025-10-15 EP claimed
US-20030104943-A1 Novel surfactants and formulations MONSANTO TECHNOLOGY LLC 2003-06-05 US claimed
US-6475953-B1 Composition and method for treating plants with exogenous chemicals MONSANTO TECHNOLOGY LLC 2002-11-05 US claimed
WO-2002069718-A2 PESTICIDE COMPOSITIONS CONTAINING OXALIC ACID MONSANTO TECHNOLOGY LLC (US) 2002-09-12 WO claimed
US-20020123430-A1 Pesticide compositions containing oxalic acid MONSANTO TECHNOLOGY LLC 2002-09-05 US claimed
EP-0936859-B1 COMPOSITION AND METHOD FOR TREATING PLANTS WITH EXOGENOUS CHEMICALS MONSANTO TECHNOLOGY LLC (US) 2002-08-28 EP claimed
US-6365551-B1 REDUCED EYE IRRITATION PROPERTIES MONSANTO TECHNOLOGY LLC 2002-04-02 US claimed
WO-2002021924-A2 HERBICIDAL COMPOSITIONS CONTAINING GLYPHOSATE AND BIPYRIDILIUM MONSANTO TECHNOLOGY LLC (US) 2002-03-21 WO claimed
CN-1332606-A Concentrated storage and transport system for glyphosate herbicide MONSANTO CO (US) 2002-01-23 CN claimed
WO-2001089302-A2 AQUEOUS PESTICIDE FORMULATIONS AND NOVEL SURFACTANTS MONSANTO TECHNOLOGY, LLC (US) 2001-11-29 WO claimed
CN-1316880-A Glyphosate formulations ZENECA LTD (GB) 2001-10-10 CN claimed