Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Glyphosate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.39 |
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.32 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.32 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glyphosate SCHEMBL18414 | 0.95 | CA12 (0.37) | CA4LMNAFOLH1CA1CA12 | |
| Glyphosate SCHEMBL3395373 | 0.95 | CA4 (0.35) | CA4LMNAFOLH1CA1CA12 | |
| Glyphosate SCHEMBL9947944 | 0.95 | CA4 (0.35) | CA4LMNAFOLH1CA1CA12 | |
| Glyphosate SCHEMBL3665222 | 0.95 | FOLH1 (0.38) | CA4LMNAFOLH1CA1CA12 | |
| Glyphosate SCHEMBL7194092 | 0.95 | CA4 (0.35) | CA4LMNAFOLH1CA1CA12 | |
| Glyphosate SCHEMBL3394676 | 0.95 | CA4 (0.35) | CA4LMNAFOLH1CA1CA12 | |
| Glyphosate SCHEMBL9756253 | 0.95 | CA4 (0.35) | CA4LMNAFOLH1CA1CA12 | |
| Glyphosate SCHEMBL3294894 | 0.93 | CA12 (0.35) | CA4LMNAFOLH1CA1CA12 | |
| Glyphosate SCHEMBL1401794 | 0.89 | FOLH1 (0.32) | CA4FOLH1FFAR3HDAC3HDAC1 | |
| Glyphosate SCHEMBL1701849 | 0.84 | BBOX1 (0.32) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2160 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260060251-A1 | HERBICIDAL AGENT COMPOSITION AND WEED CONTROL METHOD | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2026-03-05 | — | — | US | claimed |
| US-20260060254-A1 | HERBICIDAL COMPOSITIONS | BAYER AG (DE) | 2026-03-05 | — | — | US | claimed |
| US-20250318528-A1 | HERBICIDE COMPOSITION AND WEED CONTROLLING METHOD | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2025-10-16 | — | — | US | claimed |
| EP-4577047-A1 | HERBICIDAL COMPOSITIONS | Bayer Aktiengesellschaft (DE) | 2025-07-02 | — | — | EP | claimed |
| CN-118660625-A | Dithiocarbamate fungicide combinations and compositions thereof | 安道麦马克西姆有限公司 | 2024-09-17 | — | — | CN | claimed |
| WO-2024131834-A1 | HERBICIDE COMPOSITION AND USE THEREOF | 沈阳中化农药化工研发有限公司 | 2024-06-27 | — | — | WO | claimed |
| CN-118216517-A | Weeding composition and application thereof | 沈阳中化农药化工研发有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-114423287-B | Stable herbicide composition comprising amine oxide and tertiary amine | 罗地亚经营管理公司 | 2024-06-14 | — | — | CN | claimed |
| CN-114096154-B | Stable herbicide composition comprising amine oxide and betaine | 罗地亚经营管理公司 | 2024-05-28 | — | — | CN | claimed |
| CN-118019453-A | Methoxymox and glyphosate for controlling equine Tang Shucao | 巴斯夫农业化学品有限公司 | 2024-05-10 | — | — | CN | claimed |
| EP-1343375-A2 | AQUEOUS PESTICIDE FORMULATIONS AND NOVEL SURFACTANTS | Monsanto Technology LLC (US) | 2003-09-17 | — | — | EP | claimed |
| CN-1119079-C | Synergistic herbicidal compositions based on foliar-acting phosphorus-containing herbicides, imidazolinones and growth-promoting herbicides | AVENTIS CORP SCIENCE GMBH (DE) | 2003-08-27 | — | — | CN | claimed |
| US-20030104943-A1 | Novel surfactants and formulations | MONSANTO TECHNOLOGY LLC | 2003-06-05 | — | — | US | claimed |
| EP-1069826-B1 | SYNERGISTIC HERBICIDAL AGENTS BASED ON LEAF HERBICIDES CONTAINING PHOSPHORUS, IMIDAZOLINONES AND HORMONE WEED-KILLERS | BAYER CROPSCIENCE GMBH (DE) | 2003-02-19 | — | — | EP | claimed |
| US-6436874-B1 | GLUFOSINATE, BIALAPHOS, GLYPHOSATE OR SULFOSATE IN COMBINATION WITH TWO OTHER HERBICIDES | AVENTIS CROPSCIENCE GMBH (DE) | 2002-08-20 | — | — | US | claimed |
| WO-2002021924-A2 | HERBICIDAL COMPOSITIONS CONTAINING GLYPHOSATE AND BIPYRIDILIUM | MONSANTO TECHNOLOGY LLC (US) | 2002-03-21 | — | — | WO | claimed |
| WO-2001089302-A2 | AQUEOUS PESTICIDE FORMULATIONS AND NOVEL SURFACTANTS | MONSANTO TECHNOLOGY, LLC (US) | 2001-11-29 | — | — | WO | claimed |
| CN-1317931-A | Synergistic active substance combinations for controlling harmful plants | AVENTIES CROPS SCIENCES GMBH (DE) | 2001-10-17 | — | — | CN | claimed |
| CN-1295436-A | Synergistic herbicidal compositions based on phosphorus-containing foliar herbicides, imidazolinones and growth-promoting herbicides | AVENTIS CROP SCIENCE GMBH (DE) | 2001-05-16 | — | — | CN | claimed |
| US-6083878-A | Use of N-(phosphonomethyl) glycine and derivatives thereof | MONSANTO COMPANY (US) | 2000-07-04 | — | — | US | claimed |