Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17019404 | 0.76 | GAA (0.31) | GAA | |
| SCHEMBL30638028 | 0.76 | KMT2A (0.33) | — | |
| SCHEMBL26659214 | 0.75 | ALKBH1 (0.43) | — | |
| SCHEMBL17019401 | 0.75 | ALDH1A1 (0.39) | — | |
| SCHEMBL12871812 | 0.74 | RAB9A (0.44) | GAA | |
| SCHEMBL17019399 | 0.74 | — | — | |
| SCHEMBL26659287 | 0.74 | NPSR1 (0.45) | — | |
| SCHEMBL26795538 | 0.74 | KMT2A (0.38) | — | |
| SCHEMBL17019402 | 0.73 | PABPC1 (0.37) | — | |
| SCHEMBL26791926 | 0.72 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170065586-A1 | SGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2017-03-09 | — | — | US | disclosed |
| US-9487508-B2 | SGC stimulators | IRONWOOD PHARMACEUTICALS, INC. (US) | 2016-11-08 | — | — | US | disclosed |
| US-20150232461-A1 | SGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232461-A1 | SGC STIMULATORS | GUCY1B1, GUCY1A1, PRKG1 | GAA 2230/4885 |
| US-20170065586-A1 | SGC STIMULATORS | GUCY1B1, GUCY1A1, PRKG1 | GAA 2230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.