Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 9/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126690 | 0.87 | FGFR3 (0.51) | HRH3FGFR3ABL1BCRCYP17A1 | |
| SCHEMBL17023135 | 0.83 | FAAH (0.53) | HRH3FAAH | |
| SCHEMBL17023123 | 0.80 | HRH3 (0.52) | HRH3HSP90AA1FAAHBCHE | |
| SCHEMBL17023180 | 0.77 | NPC1 (0.49) | FGFR3 | |
| SCHEMBL17023106 | 0.77 | HRH3 (0.47) | HRH3FGFR3ABL1BCRKDM4E | |
| SCHEMBL17023129 | 0.76 | FGFR3 (0.46) | HSP90AA1FGFR3CYP17A1KDM4E | |
| SCHEMBL17023093 | 0.76 | FGFR3 (0.55) | HRH3FGFR3 | |
| SCHEMBL17023034 | 0.75 | FGFR3 (0.49) | HSP90AA1FGFR3CYP17A1 | |
| SCHEMBL3346853 | 0.73 | FGFR3 (0.48) | FGFR3KDM4EALDH1A1 | |
| SCHEMBL17023142 | 0.72 | FGFR3 (0.52) | HSP90AA1FGFR3CYP17A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282995-B1 | DERIVATIVES OF QUINOLINES AND QUINOXALINES AS PROTEIN TYROSINE KINASE INHIBITORS | NOVARTIS AG (CH) | 2015-08-26 | — | — | EP | claimed |