Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17023223 | 0.85 | GAA (0.48) | ADORA3ADORA1ADORA2AMEN1KMT2A | |
| SCHEMBL1876493 | 0.85 | ADORA3 (0.45) | ADORA3ADORA1ADORA2AMEN1KMT2A | |
| SCHEMBL17023233 | 0.84 | KMT2A (0.46) | ADORA3ADORA1ADORA2AMEN1KMT2A | |
| SCHEMBL17023215 | 0.83 | KDM4E (0.49) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL17023221 | 0.79 | L3MBTL1 (0.47) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL17023217 | 0.76 | LMNA (0.52) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL17023229 | 0.76 | L3MBTL1 (0.48) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL17023231 | 0.76 | LMNA (0.46) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL17023234 | 0.76 | KMT2A (0.48) | ADORA3ADORA1ADORA2AMEN1KMT2A | |
| SCHEMBL17023227 | 0.75 | L3MBTL1 (0.45) | MEN1KMT2AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059503-B1 | AMINOPYRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES CONTAINING THE SAME | KOREA RES INST CHEM TECH (KR) | 2015-08-26 | — | — | EP | claimed |