Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17023214 | 0.85 | ADORA3 (0.40) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1880366 | 0.85 | MEN1 (0.50) | GAAMEN1KMT2APOLBMAPK1 | |
| SCHEMBL17023233 | 0.84 | KMT2A (0.46) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL23005604 | 0.84 | MEN1 (0.53) | GAAMEN1KMT2APOLBMAPK1 | |
| SCHEMBL17023215 | 0.83 | KDM4E (0.49) | GAAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL17023221 | 0.79 | L3MBTL1 (0.47) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL17023217 | 0.78 | LMNA (0.52) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL17023213 | 0.76 | ADORA3 (0.35) | GAAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL17023228 | 0.76 | ALDH1A1 (0.39) | MEN1KMT2APOLBMAPK1ALDH1A1 | |
| SCHEMBL17023231 | 0.76 | LMNA (0.46) | GAAMEN1KMT2AMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059503-B1 | AMINOPYRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES CONTAINING THE SAME | KOREA RES INST CHEM TECH (KR) | 2015-08-26 | — | — | EP | claimed |