Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 2/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20135648 | 0.86 | GPR27 (0.45) | TSHRALDH1A1POLBCES2CES1 | |
| SCHEMBL17023658 | 0.81 | CA2 (0.48) | TSHRALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL67557 | 0.80 | ALDH1A1 (0.47) | TSHRFEN1ALDH1A1POLBJAK2 | |
| SCHEMBL2940225 | 0.75 | SMN1; SMN2 (0.55) | TSHRERCC5FEN1ALDH1A1TMEM97 | |
| SCHEMBL28788708 | 0.74 | TERT (0.45) | TSHRALDH1A1POLBNPC1RAB9A | |
| SCHEMBL68477 | 0.74 | NR4A1 (0.58) | ALDH1A1POLBNPC1RAB9AMEN1 | |
| SCHEMBL97298 | 0.73 | TSHR (1.00) | TSHRERCC5FEN1ALDH1A1P2RX7 | |
| SCHEMBL29904615 | 0.73 | TSHR (1.00) | TSHRERCC5FEN1ALDH1A1P2RX7 | |
| SCHEMBL57823 | 0.73 | HPGD (0.50) | TSHRERCC5FEN1ALDH1A1POLB | |
| SCHEMBL19253581 | 0.73 | MAPT (0.55) | TSHRALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778831-A | Sealing compounds, the preparation thereof, and use of same | KUNSTSTOFF- & LACKFABRIK KEMPER (DE) | 1988-10-18 | — | — | US | claimed |
| EP-0722993-B1 | Process for coating a steel plate | DAINIPPON TORYO KK (JP) | 1999-09-08 | — | — | EP | disclosed |
| EP-0722993-A1 | Process for coating a steel plate | Dai Nippon Toryo Co., Ltd. (JP) | 1996-07-24 | — | — | EP | disclosed |