SCHEMBL17029976

SCHEMBL17029976

CC(CSCC(=O)O)NC(=N)N

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.39
CYP2D6 P10635 1/20 0.38
HIF1A Q16665 1/20 0.38
MTNR1A P48039 3/20 0.33
MTNR1B P49286 3/20 0.33
BHMT Q93088 1/20 0.33
GMNN O75496 1/20 0.32
TP53 P04637 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32
CYP2C9 P11712 1/20 0.32
BLM P54132 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ITGB3 P05106 2/20 0.31
ITGA2B P08514 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17030087 0.83 BHMT (0.45) CYP2C19CYP2D6HIF1ABHMTGMNN
SCHEMBL17030085 0.83 LMNA (0.42) CYP2C19MTNR1AMTNR1BBHMTMAPT
SCHEMBL17072562 0.79 NOS3 (0.31)
SCHEMBL17030036 0.76 CYP2C19 (0.37) CYP2C19CYP2D6HIF1ABHMTGMNN
SCHEMBL17030203 0.75 MTNR1A (0.33) MTNR1AMTNR1B
SCHEMBL17224709 0.75 ITGB3 (0.48) MAPTITGB3ITGA2B
SCHEMBL17224692 0.75 ITGB3 (0.48) MAPTITGB3ITGA2B
SCHEMBL5170315 0.75 ITGB3 (0.48) MAPTITGB3ITGA2B
SCHEMBL22840759 0.74
SCHEMBL17030075 0.74 TDP1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150250217-A1 SALTY TASTE-ENHANCING AGENT AND MANUFACTURING METHOD THEREFOR, AND SALTY TASTE-ENHANCING METHOD NISSAN FOODS HOLDINGS CO., LTD. (JP) 2015-09-10 US disclosed
EP-2910130-A1 SALTY TASTE-ENHANCING AGENT AND MANUFACTURING METHOD THEREFOR, AND SALTY TASTE-ENHANCING METHOD Nissin Foods Holdings Co., Ltd. (JP) 2015-08-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150250217-A1 SALTY TASTE-ENHANCING AGENT AND MANUFACTURING METHOD THEREFOR, AND SALTY TASTE-ENHANCING METHOD TAS2R8, TAS2R13, TAS2R38 CYP2C19 4714/4885CYP2D6 4738/4885HIF1A 2719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.