Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 2/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3293002 | 0.77 | PDE10A (0.36) | TDP1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL251218 | 0.75 | PDE10A (0.35) | TDP1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL3826741 | 0.75 | ROCK1 (0.39) | ALDH1A1MEN1KMT2APDE10AMAPT | |
| SCHEMBL8665016 | 0.75 | MAPT (0.39) | TDP1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2796279 | 0.73 | ALDH1A1 (0.39) | TXNRD1TDP1ALDH1A1KMT2AMAPT | |
| SCHEMBL28940336 | 0.72 | PDE10A (0.33) | TDP1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL17674175 | 0.71 | KDM4E (0.47) | TDP1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL57064 | 0.69 | — | — | |
| SCHEMBL1425910 | 0.68 | PIN1 (0.36) | ALDH1A1KDM4EMAPTHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL17225086 | 0.67 | PDE10A (0.42) | TDP1ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120987921-A | Preparation method of pazopanib and intermediate thereof | 南京亿华药业有限公司 | 2025-11-21 | — | — | CN | disclosed |
| US-10844064-B2 | sGC stimulators | CYCLERION THERAPEUTICS, INC. (US) | 2020-11-24 | — | — | US | disclosed |
| US-10414768-B2 | Compounds for treating cystic fibrosis | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2019-09-17 | — | — | US | disclosed |
| US-9993491-B2 | Guanine riboswitch binding compounds and their use as antibiotics | SOCPRA—SCIENCES ET GÉNIE S.E.C. (CA) | 2018-06-12 | — | — | US | disclosed |
| US-20180155345-A1 | sGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2018-06-07 | — | — | US | disclosed |
| US-20170362239-A1 | COMPOUNDS FOR TREATING CYSTIC FIBROSIS | UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 (UPMC) (FR) | 2017-12-21 | — | — | US | disclosed |
| EP-3226861-A2 | COMPOUNDS FOR TREATING CYSTIC FIBROSIS | Centre National de la Recherche Scientifique (CNRS) (FR) | 2017-10-11 | — | — | EP | disclosed |
| EP-3194386-A2 | SGC STIMULATORS | Ironwood Pharmaceuticals, Inc. (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016087665-A2 | COMPOUNDS FOR TREATING CYSTIC FIBROSIS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2016-06-09 | — | — | WO | disclosed |
| WO-2016044446-A2 | SGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2016-03-24 | — | — | WO | disclosed |
| EP-0283742-A2 | Fatty acid amides as inhibitors of acyl-CoA: cholesterol acyltransferase | WARNER-LAMBERT COMPANY (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4743605-A | PREVENT ABSORPTION OF CHOLESTEROL | WARNER-LAMBERT COMPANY (US) | 1988-05-10 | — | — | US | disclosed |
| EP-0138995-A4 | REGULATION OF ENZYMES WHICH UTILIZE TETRAHYDROBIOPTERIN OR TETRAHYDROFOLATE COFACTORS WITH 6, 6-DISUBSTITUTED-TETRAHYDROPTERIDINES. | UNIV SOUTH ALABAMA (US) | 1988-05-10 | — | — | EP | disclosed |
| US-4716175-A | INHIBITION OF INTESTINAL ABSORPTION OF CHOLESTEROL | WARNER-LAMBERT COMPANY (US) | 1987-12-29 | — | — | US | disclosed |
| EP-0138995-A1 | REGULATION OF ENZYMES WHICH UTILIZE TETRAHYDROBIOPTERIN OR TETRAHYDROFOLATE COFACTORS WITH 6, 6-DISUBSTITUTED-TETRAHYDROPTERIDINES. | UNIV SOUTH ALABAMA (US) | 1985-05-02 | — | — | EP | disclosed |
| EP-0039037-B1 | PYRIMIDYLTHIO-UREAS, MEDICINES CONTAINING THEM AND THEIR USE | Beiersdorf Aktiengesellschaft (DE) | 1985-01-16 | — | — | EP | disclosed |
| WO-1984004040-A1 | REGULATION OF ENZYMES WHICH UTILIZE TETRAHYDROBIOPTERIN OR TETRAHYDROFOLATE COFACTORS WITH 6, 6-DISUBSTITUTED-TETRAHYDROPTERIDINES | UNIV SOUTH ALABAMA (US) | 1984-10-25 | — | — | WO | disclosed |
| US-4434167-A | Pyrimidyl thioureas useful for the treatment of hypertension and hyperlipidemia | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1984-02-28 | — | — | US | disclosed |
| EP-0039037-A1 | Pyrimidylthio-ureas, medicines containing them and their use | Beiersdorf Aktiengesellschaft (DE) | 1981-11-04 | — | — | EP | disclosed |
| US-4014677-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10414768-B2 | Compounds for treating cystic fibrosis | CFTR, ABCB11, SLC26A4 | TXNRD1 2098/4885TDP1 4086/4885ALDH1A1 186/4885 |
| US-20170362239-A1 | COMPOUNDS FOR TREATING CYSTIC FIBROSIS | CFTR, ABCB11, SLC26A4 | TXNRD1 2098/4885TDP1 4086/4885ALDH1A1 186/4885 |
| US-10844064-B2 | sGC stimulators | GUCY1B1, GUCY1A1, PRKG1 | TXNRD1 385/4885TDP1 1148/4885ALDH1A1 1902/4885 |
| US-20180155345-A1 | sGC STIMULATORS | GUCY1B1, GUCY1A1, PRKG1 | TXNRD1 385/4885TDP1 1148/4885ALDH1A1 1902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.