Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17047654 | 0.68 | KDM4E (0.41) | KDM4ESMN1; SMN2TP53MDM2L3MBTL1 | |
| SCHEMBL22772544 | 0.66 | KDM4E (0.35) | KDM4ECCNA2CDK2EGLN2GPR119 | |
| SCHEMBL30797258 | 0.66 | CCNA2 (0.40) | KDM4ECCNA2CDK2EGLN2TP53 | |
| SCHEMBL18766803 | 0.65 | KDM4E (0.40) | KDM4ECCNA2CDK2GPR119RXFP1 | |
| SCHEMBL22772522 | 0.62 | KDM4E (0.38) | KDM4ECCNA2CDK2TP53L3MBTL1 | |
| SCHEMBL11825277 | 0.60 | KDM4E (0.43) | KDM4ESMN1; SMN2MAT2AL3MBTL1GPR119 | |
| SCHEMBL4344306 | 0.60 | BCHE (0.43) | KDM4ECCNA2CDK2EGLN2MAT2A | |
| SCHEMBL20072041 | 0.60 | L3MBTL1 (0.45) | KDM4ETP53L3MBTL1P4HTM | |
| SCHEMBL17047671 | 0.59 | HCAR1 (0.31) | L3MBTL1P2RX7 | |
| SCHEMBL29157893 | 0.59 | KDM4E (0.46) | KDM4ESMN1; SMN2EGLN2P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110808-B1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-08-29 | — | — | EP | disclosed |
| US-9751867-B2 | Plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-05 | — | — | US | disclosed |
| US-9751867-B2 | Plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-05 | — | — | US | disclosed |
| US-9751867-B2 | Plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-05 | — | — | US | disclosed |
| EP-3110808-A1 | PLANT GROWTH REGULATING COMPOUNDS | Syngenta Participations AG (CH) | 2017-01-04 | — | — | EP | disclosed |
| US-20160368900-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-12-22 | — | — | US | disclosed |
| US-20160368900-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-12-22 | — | — | US | disclosed |
| US-20160368900-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-12-22 | — | — | US | disclosed |
| WO-2015128321-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368900-A1 | PLANT GROWTH REGULATING COMPOUNDS | GHDC, GAK, EIF4G2 | KDM4E 2890/4885CCNA2 89/4885CDK2 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.