SCHEMBL17047671

SCHEMBL17047671

CC1=C(C)C(Cl)N(c2ccsc2)C1=O

nearest known ligand 0.32

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HCAR1 Q9BXC0 1/20 0.31
MEN1 O00255 3/20 0.31
MAPT P10636 3/20 0.31
KMT2A Q03164 3/20 0.31
P2RX7 Q99572 1/20 0.31
KDM4A O75164 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KDM4C Q9H3R0 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PKM P14618 2/20 0.31
HPGD P15428 1/20 0.31
IDH1 O75874 1/20 0.31
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17047756 0.75 KMT2A (0.39) MEN1MAPTKMT2AALDH1A1HSD17B10
SCHEMBL17047745 0.71 PARP1 (0.40) HCAR1MEN1MAPTKMT2AKDM4A
SCHEMBL17047781 0.70 FAAH (0.41) MEN1KMT2A
SCHEMBL17047809 0.69 CCR1 (0.40) MEN1MAPTKMT2AALDH1A1L3MBTL1
SCHEMBL17047654 0.66 KDM4E (0.41) MEN1MAPTKMT2AALDH1A1HSD17B10
SCHEMBL21478341 0.63 MEN1 (0.38) HCAR1MEN1MAPTKMT2AALDH1A1
SCHEMBL17047692 0.60 RAB9A (0.42) MEN1MAPTKMT2AALDH1A1HSD17B10
SCHEMBL17047730 0.59 KDM4E (0.35) P2RX7L3MBTL1
SCHEMBL8980795 0.58 KMT2A (0.50) MEN1KMT2A
SCHEMBL28090496 0.58 MGLL (0.54) ALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3110808-B1 PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-08-29 EP disclosed
US-9751867-B2 Plant growth regulating compounds SYNGENTA PARTICIPATIONS AG (CH) 2017-09-05 US disclosed
US-9751867-B2 Plant growth regulating compounds SYNGENTA PARTICIPATIONS AG (CH) 2017-09-05 US disclosed
US-9751867-B2 Plant growth regulating compounds SYNGENTA PARTICIPATIONS AG (CH) 2017-09-05 US disclosed
EP-3110808-A1 PLANT GROWTH REGULATING COMPOUNDS Syngenta Participations AG (CH) 2017-01-04 EP disclosed
US-20160368900-A1 PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2016-12-22 US disclosed
US-20160368900-A1 PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2016-12-22 US disclosed
US-20160368900-A1 PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2016-12-22 US disclosed
WO-2015128321-A1 PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2015-09-03 WO disclosed
WO-2015128321-A1 PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2015-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160368900-A1 PLANT GROWTH REGULATING COMPOUNDS GHDC, GAK, EIF4G2 HCAR1 1008/4885MEN1 4325/4885MAPT 4341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.