SCHEMBL17047757

SCHEMBL17047757

CC1=CC(=O)N(c2ccccc2)C1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
KMT2A Q03164 4/20 0.38
CYP1A2 P05177 3/20 0.38
MEN1 O00255 3/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
HTT P42858 1/20 0.38
MGLL Q99685 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
MAPK1 P28482 2/20 0.36
MAPT P10636 2/20 0.36
GAA P10253 1/20 0.36
RAB9A P51151 1/20 0.36
KAT2B Q92831 2/20 0.35
LOX P28300 1/20 0.35
LOXL3 P58215 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17047714 0.78 HPGD (0.40) HPGDL3MBTL1KMT2ACYP1A2MEN1
SCHEMBL17047756 0.72 KMT2A (0.39) HPGDKMT2ACYP1A2MEN1CYP2C9
SCHEMBL21910199 0.67 ALDH1A1 (0.45) HPGDL3MBTL1KMT2ACYP1A2MEN1
SCHEMBL17047731 0.67 GAA (0.36) HPGDKMT2ACYP1A2MEN1CYP2C9
SCHEMBL11206667 0.66 HSD11B1 (0.41) KMT2ACYP1A2MEN1CYP2C9CYP2C19
SCHEMBL6713101 0.65 MAOA (0.48) HPGDL3MBTL1KMT2ACYP1A2MEN1
SCHEMBL8791220 0.64 HSD11B1 (0.50) SMN1; SMN2HSD11B1
SCHEMBL10712319 0.64 CYP1A2 (0.37) KMT2ACYP1A2MEN1CYP2C9CYP2C19
SCHEMBL17047781 0.63 FAAH (0.41) KMT2AMEN1MGLLSMN1; SMN2
SCHEMBL9835334 0.63 MAOA (0.47) HPGDL3MBTL1KMT2ACYP1A2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3110808-B1 PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-08-29 EP disclosed
US-9751867-B2 Plant growth regulating compounds SYNGENTA PARTICIPATIONS AG (CH) 2017-09-05 US disclosed
US-9751867-B2 Plant growth regulating compounds SYNGENTA PARTICIPATIONS AG (CH) 2017-09-05 US disclosed
US-9751867-B2 Plant growth regulating compounds SYNGENTA PARTICIPATIONS AG (CH) 2017-09-05 US disclosed
EP-3110808-A1 PLANT GROWTH REGULATING COMPOUNDS Syngenta Participations AG (CH) 2017-01-04 EP disclosed
US-20160368900-A1 PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2016-12-22 US disclosed
US-20160368900-A1 PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2016-12-22 US disclosed
US-20160368900-A1 PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2016-12-22 US disclosed
WO-2015128321-A1 PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2015-09-03 WO disclosed
WO-2015128321-A1 PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2015-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160368900-A1 PLANT GROWTH REGULATING COMPOUNDS GHDC, GAK, EIF4G2 HPGD 769/4885L3MBTL1 4013/4885KMT2A 3798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.