Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 5/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15735322 | 0.90 | CA1 (0.54) | CA1FABP3DGKAGPR84CES2 | |
| SCHEMBL29078967 | 0.90 | CA1 (0.54) | CA1FABP3DGKAGPR84CES2 | |
| Potassium Ion SCHEMBL29185344 | 0.87 | FABP3 (0.55) | CA1FABP3DGKACES2CES1 | |
| Dodecanoic Anhydride SCHEMBL18166491 | 0.85 | CA1 (0.61) | CA1FABP3DGKACES2CES1 | |
| Propionic Acid SCHEMBL28401062 | 0.82 | DGKA (0.47) | CA1FABP3DGKAMAPTCES2 | |
| Glycine SCHEMBL29130105 | 0.82 | DGKA (0.47) | CA1FABP3DGKAMAPTCES2 | |
| Behenic Acid SCHEMBL3344680 | 0.81 | FABP3 (0.61) | CA1FABP3CES2CES1 | |
| SCHEMBL446588 | 0.81 | FABP3 (0.70) | FABP3MAPTLMNA | |
| SCHEMBL2698113 | 0.81 | FABP3 (0.70) | FABP3MAPTLMNA | |
| Propionic Acid SCHEMBL28481898 | 0.80 | DGKA (0.52) | CA1FABP3DGKACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120321576-A1 | SUNSCREEN COMPOSITION | SHISEIDO COMPANY, LTD. (JP) | 2012-12-20 | — | — | US | claimed |
| CN-115105432-B | External skin preparation composition | 株式会社资生堂 | 2025-02-11 | — | — | CN | disclosed |
| CN-118510491-A | Expression of silk-stimulated collagen and seal protein-1 and silk-stimulated anti-inflammatory effects | 自然进化公司 | 2024-08-16 | — | — | CN | disclosed |
| US-20240148622-A1 | TOPICAL COMPOSITION FOR SKIN | SHISEIDO COMPANY, LTD. (JP) | 2024-05-09 | — | — | US | disclosed |
| US-11964043-B2 | Method of emulsification using core-corona type microparticles | SHISEIDO COMPANY, LTD. (JP) | 2024-04-23 | — | — | US | disclosed |
| WO-2024059119-A2 | COMPOUNDS AND THEIR USE IN FILTERING ULTRAVIOLET AND/OR HIGH-ENERGY VISIBLE LIGHT | SOLIOME, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| WO-2024059862-A2 | FIBROIN PEPTIDES AND PROTEIN FRAGMENTS COMPOSITIONS | EVOLVED BY NATURE, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| US-11931448-B2 | Water-in-oil type emulsion composition | SHISEIDO COMPANY, LTD. (JP) | 2024-03-19 | — | — | US | disclosed |
| EP-4301790-A1 | SUNSCREENS DERIVED FROM KYNURENINES AND OTHER UV-ABSORBING OXIDIZED AMINO ACIDS BOUND TO PEPTIDES OR POLYMERS | The Trustees Of Princeton University (US) | 2024-01-10 | — | — | EP | disclosed |
| EP-3520772-B1 | COSMETIC RAW MATERIAL USING CORE-CORONA TYPE MICROPARTICLES AND OIL-IN-WATER TYPE EMULSION COSMETIC | SHISEIDO CO LTD (JP) | 2023-12-20 | — | — | EP | disclosed |
| US-6602513-B2 | Containing dextrin | SHISEIDO CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| US-20030091603-A1 | Skin preparations for external use | SHISEIDO COMPANY, LTD. (JP) | 2003-05-15 | — | — | US | disclosed |
| EP-0728469-B1 | An endermic liniment | SHISEIDO CO LTD (JP) | 2003-01-15 | — | — | EP | disclosed |
| US-20020018793-A1 | FACE PACK | SHISEIDO COMPANY, LTD. (JP) | 2002-02-14 | — | — | US | disclosed |
| EP-1153602-A1 | SKIN PREPARATIONS FOR EXTERNAL USE | SHISEIDO COMPANY LIMITED (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-6169114-B1 | STORAGE STABILITY, THIOL COMPOUND IS ONE OR MORE TYPES OF CYSTEINE AND ITS DERIVATIVES, ZINC OXIDE HAVING A WATER REPELLANT TREATMENT ON ITS SURFACE, | SHISEIDO COMPANY, LTD. (JP) | 2001-01-02 | — | — | US | disclosed |
| EP-0976381-A1 | DERMATOLOGIC PREPARATION | SHISEIDO COMPANY LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |
| EP-0970681-A1 | FACE PACK | SHISEIDO COMPANY LIMITED (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5767158-A | FOR BLEACHING SKIN | SHISEIDO CO., LTD. (JP) | 1998-06-16 | — | — | US | disclosed |
| EP-0728469-A2 | An endermic liniment | SHISEIDO COMPANY LIMITED (JP) | 1996-08-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030091603-A1 | Skin preparations for external use | CUTA, POLR1C, ACMSD | CA1 2923/4885FABP3 2827/4885DGKA 2720/4885 |
| US-11964043-B2 | Method of emulsification using core-corona type microparticles | LIPA, CORO1A, CLTA | CA1 1981/4885FABP3 164/4885DGKA 1457/4885 |
| US-11931448-B2 | Water-in-oil type emulsion composition | FAM83A, LIPA, CUTA | CA1 3704/4885FABP3 632/4885DGKA 382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.