Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3763795 | 1.00 | SLC6A3 (0.38) | SLC6A3HPGDKDM4EALDH1A1GLA | |
| SCHEMBL15121580 | 0.89 | PTGS2 (0.31) | SLC6A3ALDH1A1GAA | |
| SCHEMBL15121579 | 0.89 | PTGS2 (0.31) | SLC6A3ALDH1A1GAA | |
| SCHEMBL3770516 | 0.89 | ABCC1 (0.41) | HPGDKDM4EALDH1A1GAALMNA | |
| SCHEMBL3770518 | 0.89 | ABCC1 (0.41) | HPGDKDM4EALDH1A1GAALMNA | |
| SCHEMBL3764060 | 0.78 | SLC6A3 (0.38) | SLC6A3HPGDKDM4EALDH1A1GLA | |
| SCHEMBL14353834 | 0.78 | SLC6A3 (0.38) | SLC6A3HPGDKDM4EALDH1A1GLA | |
| SCHEMBL3764062 | 0.78 | SLC6A3 (0.38) | SLC6A3HPGDKDM4EALDH1A1GLA | |
| SCHEMBL3770137 | 0.78 | MEP1B (0.31) | SLC6A3 | |
| SCHEMBL1703056 | 0.78 | MEP1B (0.31) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440526-B1 | 3-HALO-6-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2014-11-12 | — | — | EP | disclosed |
| US-8598086-B2 | 3-halo-(arly)-4-iminotetrahydropicolinates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2013-12-03 | — | — | US | disclosed |
| EP-2440530-B1 | PROCESS FOR THE PREPARATION OF 6-(ARYL)-4-AMINOPICOLINATES | DOW AGROSCIENCES LLC (US) | 2013-07-24 | — | — | EP | disclosed |
| US-8252938-B2 | Process for the preparation of 6-(aryl)-4-aminopicolinates | DOW AGROSCIENCES, LLC. (US) | 2012-08-28 | — | — | US | disclosed |
| EP-2440530-A1 | PROCESS FOR THE PREPARATION OF 6-(ARYL)-4-AMINOPICOLINATES | Dow AgroSciences LLC (US) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010144380-A1 | PROCESS FOR THE PREPARATION OF 6-(ARYL)-4-AMINOPICOLINATES | DOW AGROSCIENCES LLC (US) | 2010-12-16 | — | — | WO | disclosed |
| US-20100311981-A1 | PROCESS FOR THE PREPARATION OF 6-(ARYL)-4-AMINOPICOLINATES | DOW AGROSCIENCES LLC (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100311594-A1 | 3-HALO-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311981-A1 | PROCESS FOR THE PREPARATION OF 6-(ARYL)-4-AMINOPICOLINATES | HTR6, CYP46A1, NISCH | SLC6A3 223/4885HPGD 1088/4885KDM4E 2875/4885 |
| US-20100311594-A1 | 3-HALO-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | HDHD5, ATL3, HCAR3 | SLC6A3 33/4885HPGD 2956/4885KDM4E 3033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.