SCHEMBL170570

SCHEMBL170570

O=C(NCCn1nccn1)OCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
HTT P42858 1/20 0.57
KAT2B Q92831 1/20 0.54
TGM2 P21980 1/20 0.51
GAA P10253 1/20 0.51
KEAP1 Q14145 3/20 0.50
NFE2L2 Q16236 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
POLB P06746 1/20 0.50
MAPT P10636 1/20 0.49
SLC1A3 P43003 1/20 0.48
SLC1A1 P43005 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
IDO1 P14902 2/20 0.46
ANPEP P15144 1/20 0.46
TDO2 P48775 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13055383 0.81 LMNA (0.80) LMNASMN1; SMN2HTTKAT2BTGM2
SCHEMBL17346752 0.79 LMNA (0.63) LMNASMN1; SMN2HTTKAT2BTGM2
SCHEMBL7159219 0.79 LMNA (0.63) LMNASMN1; SMN2HTTKAT2BTGM2
SCHEMBL17885358 0.79 SMN1; SMN2 (0.49) LMNASMN1; SMN2HTTKAT2BTGM2
SCHEMBL31517255 0.79 LMNA (0.55) LMNASMN1; SMN2HTTKAT2BTGM2
SCHEMBL28473741 0.79 SMN1; SMN2 (0.56) LMNASMN1; SMN2HTTKAT2BPOLB
SCHEMBL17885357 0.78 SMN1; SMN2 (0.48) LMNASMN1; SMN2HTTKAT2BTGM2
SCHEMBL18254066 0.78 HTT (0.81) LMNASMN1; SMN2HTTTGM2KEAP1
SCHEMBL8895244 0.77 LMNA (0.73) LMNASMN1; SMN2HTTKAT2BTGM2
Benzyl Phenethylcarbamate SCHEMBL4287199 0.77 LMNA (0.73) LMNASMN1; SMN2HTTTGM2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9918473-B2 Use of aryl carbamates in agriculture and other plant-related areas North Carolian State University (US) 2018-03-20 US disclosed
US-9918473-B2 Use of aryl carbamates in agriculture and other plant-related areas North Carolian State University (US) 2018-03-20 US disclosed
US-9918473-B2 Use of aryl carbamates in agriculture and other plant-related areas North Carolian State University (US) 2018-03-20 US disclosed
US-20160353739-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS UNIV NORTH CAROLINA STATE (US) 2016-12-08 US disclosed
US-20160353739-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS UNIV NORTH CAROLINA STATE (US) 2016-12-08 US disclosed
US-20160353739-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS UNIV NORTH CAROLINA STATE (US) 2016-12-08 US disclosed
US-9439436-B2 Use of aryl carbamates in agriculture and other plant-related areas NORTH CAROLINA STATE UNIVERSITY (US) 2016-09-13 US disclosed
US-9439436-B2 Use of aryl carbamates in agriculture and other plant-related areas NORTH CAROLINA STATE UNIVERSITY (US) 2016-09-13 US disclosed
US-9439436-B2 Use of aryl carbamates in agriculture and other plant-related areas NORTH CAROLINA STATE UNIVERSITY (US) 2016-09-13 US disclosed
US-20150327552-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS UNIV NORTH CAROLINA STATE (US) 2015-11-19 US disclosed
US-20130172187-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS NORTH CAROLINA STATE UNIVERSITY 2013-07-04 US disclosed
US-20130172187-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS NORTH CAROLINA STATE UNIVERSITY 2013-07-04 US disclosed
US-20130172187-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS NORTH CAROLINA STATE UNIVERSITY 2013-07-04 US disclosed
US-20130123225-A1 INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES NORTH CAROLINA STATE UNIVERSITY 2013-05-16 US disclosed
US-20130123225-A1 INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES NORTH CAROLINA STATE UNIVERSITY 2013-05-16 US disclosed
US-20130123225-A1 INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES NORTH CAROLINA STATE UNIVERSITY 2013-05-16 US disclosed
WO-2012030986-A2 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS NORTH CAROLINA STATE UNIVERSITY (US) 2012-03-08 WO disclosed
WO-2012030986-A2 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS NORTH CAROLINA STATE UNIVERSITY (US) 2012-03-08 WO disclosed
WO-2012006276-A1 INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES NORTH CAROLINA STATE UNIVERSITY (US) 2012-01-12 WO disclosed
WO-2012006276-A1 INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES NORTH CAROLINA STATE UNIVERSITY (US) 2012-01-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130172187-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS CTRC, ACE, DDT LMNA 4641/4885SMN1; SMN2 4442/4885HTT 584/4885
US-20160353739-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS CTRC, ACE, DDT LMNA 4641/4885SMN1; SMN2 4442/4885HTT 584/4885
US-20130123225-A1 INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES PGLS, BLVRB, AADAC LMNA 4530/4885SMN1; SMN2 4883/4885HTT 1201/4885
US-20150327552-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS CTRC, ACE, DDT LMNA 4641/4885SMN1; SMN2 4442/4885HTT 584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.