SCHEMBL17346752

SCHEMBL17346752

O=C(NCCn1c(=O)n(CCNC(=O)OCc2ccccc2)c(=O)n(CCNC(=O)OCc2ccccc2)c1=O)OCc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
HTT P42858 1/20 0.60
KAT2B Q92831 1/20 0.60
TGM2 P21980 1/20 0.53
GAA P10253 1/20 0.53
KEAP1 Q14145 3/20 0.52
NFE2L2 Q16236 3/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
MAPT P10636 1/20 0.51
IDO1 P14902 2/20 0.50
SLC1A3 P43003 1/20 0.50
SLC1A1 P43005 1/20 0.50
TDO2 P48775 1/20 0.50
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
PRSS1 P07477 1/20 0.47
PRSS2 P07478 1/20 0.47
ELANE P08246 1/20 0.47
PRSS3 P35030 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13055383 0.84 LMNA (0.80) LMNASMN1; SMN2HTTKAT2BTGM2
SCHEMBL7159219 0.82 LMNA (0.63) LMNASMN1; SMN2HTTKAT2BTGM2
SCHEMBL18254066 0.80 HTT (0.81) LMNASMN1; SMN2HTTTGM2KEAP1
SCHEMBL31311383 0.80 KAT2B (0.58) LMNASMN1; SMN2HTTKAT2BTGM2
SCHEMBL2402780 0.80 HTT (0.74) LMNASMN1; SMN2HTTTGM2KEAP1
SCHEMBL170570 0.79 LMNA (0.60) LMNASMN1; SMN2HTTKAT2BTGM2
SCHEMBL29889023 0.79 SMN1; SMN2 (0.56) LMNASMN1; SMN2HTTKAT2BTGM2
SCHEMBL375858 0.79 LMNA (0.73) LMNASMN1; SMN2HTTKAT2BTGM2
SCHEMBL9874334 0.79 HTT (0.79) LMNASMN1; SMN2HTTTGM2KEAP1
SCHEMBL8895244 0.79 LMNA (0.73) LMNASMN1; SMN2HTTKAT2BTGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10457792-B2 Polarizing plate protective film, polarizing plate, and display device FUJIFILM CORPORATION (JP) 2019-10-29 US disclosed
US-10338290-B2 Cellulose ester film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2019-07-02 US disclosed
US-10338277-B2 Polarizing plate protective film, polarizing plate, and display FUJIFILM CORPORATION (JP) 2019-07-02 US disclosed
US-10040754-B2 Cellulose acylate film, novel compound, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2018-08-07 US disclosed
US-10031264-B2 Polarizing plate and display device FUJIFILM CORPORATION (JP) 2018-07-24 US disclosed
US-9817156-B2 Polarizing plate protective film, polarizing plate and display device FUJIFILM CORPORATION (JP) 2017-11-14 US disclosed
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-9678249-B2 Polarizing plate protective film, polarizing plate and display device FUJIFILM CORPORATION (JP) 2017-06-13 US disclosed
US-20160291210-A1 POLARIZING PLATE AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160291211-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160291213-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160178809-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-06-23 US disclosed
US-20160060405-A1 POLYMER FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-03-03 US disclosed
US-20150361036-A1 CELLULOSE ACYLATE FILM, NOVEL COMPOUND, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10040754-B2 Cellulose acylate film, novel compound, polarizing plate and liquid crystal display device NR1D1, NR1H2, NR1D2 LMNA 1344/4885SMN1; SMN2 3280/4885HTT 4251/4885
US-10457792-B2 Polarizing plate protective film, polarizing plate, and display device NBAS, SSB, GNA15 LMNA 156/4885SMN1; SMN2 2279/4885HTT 4332/4885
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE NBAS, SSB, BIRC5 LMNA 182/4885SMN1; SMN2 2393/4885HTT 4534/4885
US-20150361036-A1 CELLULOSE ACYLATE FILM, NOVEL COMPOUND, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE NR1D1, NR1H2, NR1D2 LMNA 1344/4885SMN1; SMN2 3280/4885HTT 4251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.