Maritimein

Maritimein

SCHEMBL1706313

O=C1C(=Cc2ccc(O)c(O)c2)Oc2c1ccc(O[C@@H]1OC(CO)[C@@H](O)[C@H](O)C1O)c2O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 1.00
KMT2A Q03164 1/20 1.00
CDK5 Q00535 1/20 0.64
CDK5R1 Q15078 1/20 0.64
APP P05067 1/20 0.57
GAA P10253 2/20 0.57
TDP1 Q9NUW8 1/20 0.57
PTPN1 P18031 3/20 0.49
HIF1A Q16665 1/20 0.45
KDM4E B2RXH2 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
G6PD P11413 1/20 0.44
MAPK1 P28482 1/20 0.44
ADRA1A P35348 1/20 0.44
PTGS2 P35354 1/20 0.44
PARP1 P09874 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maritimein SCHEMBL29354648 1.00 MEN1 (1.00) MEN1KMT2ACDK5CDK5R1APP
Maritimein SCHEMBL1706306 1.00 MEN1 (1.00) MEN1KMT2ACDK5CDK5R1APP
SCHEMBL31360843 0.89 MEN1 (0.81) MEN1KMT2ACDK5CDK5R1APP
SCHEMBL1098173 0.89 MEN1 (0.81) MEN1KMT2ACDK5CDK5R1APP
Maritimein SCHEMBL7203694 0.85 MEN1 (0.73) MEN1KMT2ACDK5CDK5R1TDP1
SCHEMBL12405921 0.83 MEN1 (0.71) MEN1KMT2AGAATDP1PTPN1
Sulfurein SCHEMBL29462894 0.83 CDK5 (0.77) MEN1KMT2ACDK5CDK5R1GAA
Sulfurein SCHEMBL2817568 0.83 CDK5 (0.77) MEN1KMT2ACDK5CDK5R1GAA
SCHEMBL1043781 0.80 CDK5 (0.80) MEN1KMT2ACDK5CDK5R1GAA
SCHEMBL13324395 0.79 MEN1 (0.66) MEN1KMT2ACDK5CDK5R1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11712056-B2 Extract obtained from several plants for use in the prevention and/or treatment of chronic inflammatory bowel diseases VALBIOTIS (FR) 2023-08-01 US claimed
EP-3982924-B1 PLANT EXTRACT MIXTURE FOR USE IN THE PREVENTION AND/OR TREATMENT OF CHRONIC INFLAMMATORY BOWEL DISEASES VALBIOTIS (FR) 2023-07-26 EP claimed
US-20220257685-A1 PLANT EXTRACT MIXTURE FOR USE IN THE PREVENTION AND/OR TREATMENT OF CHRONIC INFLAMMATORY BOWEL DISEASES VALBIOTIS (FR) 2022-08-18 US claimed
EP-4039332-A1 METHOD OF EXTRACTION AND ENRICHMENT OF MONOGLYCOSYLATED FLAVONOIDS FROM CHRYSANTHELLUM INDICUM FOR THE TREATMENT OF INFLAMMATORY-BASED POLYARTHRITIC DISORDERS, FOR USE IN COSMETIC, NUTRACEUTICAL AND MEDICAL DEVICES AND PHARMACEUTICAL APPLICATIONS Phytoitalia SRL (IT) 2022-08-10 EP claimed
EP-3533454-B1 COMPOSITION COMPRISING A MIXTURE OF PLANT EXTRACTS OR A MIXTURE OF MOLECULES CONTAINED IN SAID PLANTS AND USE TO ACT ON THE CARBOHYDRATE AND/OR LIPID METABOLISM VALBIOTIS (FR) 2022-04-20 EP claimed
EP-3982924-A1 PLANT EXTRACT MIXTURE FOR USE IN THE PREVENTION AND/OR TREATMENT OF CHRONIC INFLAMMATORY BOWEL DISEASES Valbiotis (FR) 2022-04-20 EP claimed
US-20200359670-A1 EXTRACT OBTAINED FROM SEVERAL PLANTS FOR USE IN THE PREVENTION AND/OR TREATMENT OF CHRONIC INFLAMMATORY BOWEL DISEASES UNIVERSITE CLERMONT AUVERGNE (FR) 2020-11-19 US claimed
US-10736930-B2 Compositions and methods for controlling carbohydrate and fat metabolism VALBIOTIS (FR) 2020-08-11 US claimed
EP-3332793-B1 COMPOSITION COMPRISING A MIXTURE OF PLANT EXTRACTS OR A MIXTURE OF MOLECULES CONTAINED IN SAID PLANTS AND USE TO ACT ON THE CARBOHYDRATE AND/OR LIPID METABOLISM VALBIOTIS (FR) 2020-03-18 EP claimed
EP-3209315-B1 COMPOSITION CONTAINING A MIXTURE OF PLANT EXTRACTS OR A MIXTURE OF MOLECULES CONTAINED IN SAID PLANTS, AND USE FOR CONTROLLING GLUCIDE AND/OR LIPID METABOLISM VALBIOTIS (FR) 2019-04-24 EP claimed
US-20160106793-A1 COMPOSITIONS AND METHODS FOR CONTROLING CARBOHYDRATE AND FAT METABOLISM UNIVERSITE CLERMONT AUVERGNE (FR) 2016-04-21 US claimed
US-20140088030-A1 WATER SOLUBLE AND ACTIVABLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS AND PROCESS FOR PREPARING SAID DERIVATIVES LIBRAGEN (FR) 2014-03-27 US claimed
EP-2027279-B1 Phenolic compounds with cosmetic and therapeutic applications LIBRAGEN (FR) 2012-04-18 EP claimed
EP-2379576-A1 HYDROSOLUBLE [6)-O-alpha-D-GLCP-(1->]n-6-O-beta-D-GLCP-(1->-PHENOLIC DERIVATIVES WITH DERMOCOSMETIC, NUTRITIONAL AND THERAPEUTIC APPLICATIONS, AND COMPOSITIONS CONTAINING SAID WATER SOLUBLE COMPOUNDS Libragen (FR) 2011-10-26 EP claimed
WO-2010072754-A1 HYDROSOLUBLE [6)O-α-D-GLCP-(1→]n-6-O-β-D-GLCP-(1→-PHENOLIC DERIVATIVES WITH DERMOCOSMETIC, NUTRITIONAL AND THERAPEUTIC APPLICATIONS, AND COMPOSITIONS CONTAINING SAID WATER SOLUBLE COMPOUNDS LIBRAGEN (FR) 2010-07-01 WO claimed
CN-101611148-A Water-soluble phenolic derivatives for cosmetic and therapeutic applications on the skin LIBRAGEN (FR) 2009-12-23 CN claimed
EP-2027279-A2 WATER SOLUBLE AND ACTIVABLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS AND PROCESS FOR PREPARING SAID DERIVATIVES Libragen (FR) 2009-02-25 EP claimed
WO-2007144368-A2 WATER SOLUBLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS LIBRAGEN (FR) 2007-12-21 WO claimed
US-6872771-B1 Tire with rubber containing flavone THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-29 US claimed
EP-0317453-B1 MEDICINAL COMPOSITIONS BASED ON FLAVONOIDS AND SAPONINS EXTRACTED FROM CHRYSANTHELLUM, PROCESS FOR THEIR MANUFACTURE AND THERAPEUTICAL USES IPHYM SA Société Anonyme dite : (FR) 1993-02-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160106793-A1 COMPOSITIONS AND METHODS FOR CONTROLING CARBOHYDRATE AND FAT METABOLISM PLIN3, GYS1, PLIN5 MEN1 2817/4885KMT2A 2866/4885CDK5 1878/4885
US-20140088030-A1 WATER SOLUBLE AND ACTIVABLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS AND PROCESS FOR PREPARING SAID DERIVATIVES UGGT1, TYR, G6PD MEN1 4300/4885KMT2A 1919/4885CDK5 3264/4885
US-10736930-B2 Compositions and methods for controlling carbohydrate and fat metabolism CPT1A, PC, PCK1 MEN1 4051/4885KMT2A 2350/4885CDK5 2603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.